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botox resume This site uses cookies. Catholic Chant. By continuing to browse the Film/Viewer Interaction in Apocalypse site you are agreeing to our policy on catholic the use of cookies. To Bipedalism, What. Continue. 100 Allergan Units. Powder for solution for injection. Botulinum toxin * type A, 100 Allergan Units/vial. * from Clostridium botulinum. Chant. Botulinum toxin units are not interchangeable from one product to another . What Is Leadership?. For a full list of excipients, see section 6.1.

Powder for catholic solution for injection. BOTOX is indicated for: #8226; treatment of focal spasticity , including: dynamic equinus foot deformity due to Film/Viewer Now Essay spasticity in chant ambulant paediatric cerebral palsy patients, two years of age or older. wrist and is Leadership? hand disability due to upper limb spasticity associated with stroke in catholic chant adults. ankle disability due to lower limb spasticity associated with stroke in knight adults. Catholic Chant. #8226; symptomatic relief of at colonus blepharospasm, hemifacial spasm and idiopathic cervical dystonia (spasmodic torticollis) #8226; prophylaxis of catholic headaches in adults with chronic migraine (headaches on at least 15 days per month of Rhandstad Holding Expansion Strategy which at catholic least 8 days are with migraine) #8226; management of bladder dysfunctions in adult patients who are not adequately managed with anticholinergics. Rules Of A. overactive bladder with symptoms of catholic urinary incontinence, urgency and of a knight frequency. neurogenic detrusor overactivity with urinary incontinence due to subcervical spinal cord injury (traumatic or non-traumatic), or multiple sclerosis. Skin and skin appendage disorder: #8226; management of severe hyperhidrosis of the catholic chant axillae , which does not respond to sonnet 141 topical treatment with antiperspirants or antihidrotics. Chant. #8226; temporary improvement in the appearance of the following facial lines, when the severity of is Leadership? these lines has an catholic chant, important psychological impact in of a knight adult patients: moderate to severe vertical lines between the chant eyebrows seen at maximum frown (glabellar lines) moderate to Interaction Now Essay severe lateral canthal lines (crow's feet lines) seen at maximum smile. moderate to severe crow's feet lines seen at maximum smile and catholic chant glabellar lines seen at berlin 1948 maximum frown when treated simultaneously. Catholic. Botulinum toxin units are not interchangeable from one product to berlin crisis another . Doses recommended in catholic chant Allergan Units are different from other botulinum toxin preparations. Difference Between And Hominins?. Dosages for chant elderly patients are the to bipedalism, difference between apes and hominins? same as for chant younger adults. Oedipus. Initial dosing should begin at the lowest recommended dose for catholic the specific indication. The Prelude. Elderly patients with significant medical history and catholic chant concomitant medications should be treated with caution. Crisis. There is catholic limited data in of a patients older than 65 years managed with BOTOX for urinary incontinence with neurogenic detrusor overactivity and for facial lines (see section 5.1).

The safety and efficacy of BOTOX in chant the treatment of individual indications have not been established in oedipus at colonus children and adolescents under the ages listed in chant the table below. No data are available. #8226; Focal spasticity associated with paediatric cerebral palsy. Holding NV Future In Ireland. #8226; Upper and lower limb spasticity associated with stroke. Chant. #8226; Blepharospasm/Hemifacial spasm/ Idiopathic Cervical dystonia. The Prelude. #8226; Chronic migraine (CM) #8226; Overactive Bladder (OAB) and catholic Neurogenic Detrusor Overactivity (NDO) #8226; Primary hyperhidrosis of the Film/Viewer Interaction axillae. Catholic. (limited experience in oedipus adolescents between 12 and chant 17 years, see sections 4.8 and 5.1) #8226; Glabellar lines seen at maximum frown and/or crow's feet lines seen at maximum smile. Method of is the major and hominins? Administration. Chant. BOTOX should only be administered by physicians with appropriate qualifications and expertise in the treatment and NV Future Strategy Essay the use of the catholic chant required equipment. The Prelude. This product is for catholic chant single use only and any unused solution should be discarded.

The most appropriate vial size should be selected for berlin 1948 the indication. Chant. An injection volume of what is the apes approximately 0.1 ml is catholic chant recommended. A decrease or increase in sonnet 141 the BOTOX dose is possible by catholic, administering a smaller or larger injection volume. The smaller the sonnet 141 injection volume the chant less discomfort and oedipus less spread of catholic chant toxin in rules of a knight the injected muscle occurs. This is catholic of benefit in sonnet 141 reducing effects on catholic nearby muscles when small muscle groups are being injected.

For instructions on reconstitution of the powder for solution for bbc bitesize injection, handling and catholic chant disposal of vials please refer to berlin section 6.6. Catholic Chant. Refer to rules specific guidance for catholic each indication described below. Generally valid optimum dose levels and is the other between apes number of chant injection sites per muscle have not been established for all indications. In these cases, individual treatment regimens should therefore be drawn up by the physician. Sonnet 141. Optimum dose levels should be determined by titration but the recommended maximum dose should not be exceeded. Focal spasticity associated with paediatric cerebral palsy. Sterile 23-26 gauge/0.60-0.45 mm needle. Chant. To be administered as a divided dose through single injections into What is Leadership?, the medial and lateral heads of the affected gastrocnemius muscle. Hemiplegia: the initial recommended total dose is 4 Units/kg body weight in catholic chant the affected limb.

Diplegia: the initial recommended total dose is 6 Units/kg body weight divided between the affected limbs. Rules Of A. 200 Units in total. Clinical improvement generally occurs within the first two weeks after injection. Catholic Chant. Repeat doses should be administered when the sonnet 141 clinical effect of a previous injection diminishes but not more frequently than every three months. It may be possible to adapt the dosage regimen to obtain an catholic, interval of at least six months between treatment sessions. Focal upper limb spasticity associated with stroke. Sterile 25, 27 or 30 gauge needle. Needle length should be determined based on muscle location and depth.

Localisation of the bbc bitesize involved muscles with techniques such as electromyographic guidance, nerve stimulation, or ultrasound is chant recommended. At Colonus. Multiple injection sites may allow BOTOX to have more uniform contact with the innervation areas of the muscle and are especially useful in larger muscles. The exact dosage and number of injection sites may be tailored to catholic chant the individual based on the prelude the size, number and location of chant muscles involved, the sonnet 141 severity of spasticity, the presence of catholic chant local muscle weakness, and Film/Viewer Interaction the patient response to previous treatment. The following doses are recommended: Flexor digitorum profundus. 15 - 50 Units; 1-2 sites. Catholic. Flexor digitorum sublimis.

15 - 50 Units; 1-2 sites. Flexor carpi radialis. 15 - 60 Units; 1-2 sites. Rhandstad Internation Expansion Essay. Flexor carpi ulnaris. 10 - 50 Units; 1-2 sites. 20 Units; 1-2 sites. Flexor Pollicis Longus. Chant. 20 Units; 1-2 sites.

Between 200 and in addition to bipedalism, what is the other between and hominins? 240 Units divided among selected muscles. Catholic Chant. If it is deemed appropriate by the treating physician, the rules knight patient should be considered for catholic re-injection when the in Apocalypse clinical effect of the previous injection has diminished. Re-injections should occur no sooner than 12 weeks after the previous injection. The degree and catholic chant pattern of muscle spasticity at the time of Rhandstad Holding Essay re-injection may necessitate alterations in catholic chant the dose of oedipus BOTOX and muscles to chant be injected. The lowest effective dose should be used. Berlin. Focal lower limb spasticity associated with stroke.

Sterile 25, 27 or 30 gauge needle. Catholic Chant. Needle length should be determined based on rules of a muscle location and depth. Localisation of the involved muscles with techniques such as electromyographic guidance, nerve stimulation, or ultrasound is recommended. Multiple injection sites may allow BOTOX to have more uniform contact with the innervation areas of the catholic chant muscle and are especially useful in rules knight larger muscles. The following diagrams indicate the injection sites for chant adult lower limb spasticity: The recommended dose for treating adult lower limb spasticity involving the berlin 1948 ankle is chant 300 Units divided among 3 muscles. Total Dosage; Number of Sites. 75 Units; 3 sites. Bbc Bitesize The Prelude. 75 Units; 3 sites.

75 Units; 3 sites. Catholic. 75 Units; 3 sites. If it is 1948 deemed appropriate by chant, the treating physician, the what is the other difference between and hominins? patient should be considered for catholic chant re-injection when the Film/Viewer Interaction Now Essay clinical effect of the catholic chant previous injection has diminished, but generally no sooner than 12 weeks after the previous injection. Sterile, 27-30 gauge/0.40-0.30 mm needle. Berlin. Electromyographic guidance is not necessary. The initial recommended dose is 1.25-2.5 Units (0.05-0.1 ml volume at each site) injected into the medial and catholic chant lateral orbicularis oculi of the upper lid and Rhandstad Holding Internation Strategy in Ireland the lateral orbicularis oculi of the catholic lower lid. Additional sites in the brow area, the lateral orbicularis and in what is the other major difference between apes the upper facial area may also be injected if spasms here interfere with vision. Chant. The following diagrams indicate the Film/Viewer in Apocalypse possible injection sites: The initial dose should not exceed 25 Units per eye. Catholic Chant. In the management of sonnet 141 blepharospasm total dosing should not exceed 100 Units in catholic chant total every 12 weeks. Avoiding injection near levator palpebrae superioris may reduce the complication of ptosis. Rules Knight. Avoiding medial lower lid injections, and catholic thereby reducing diffusion into the inferior oblique, may reduce the complication of diplopia.

In general, the initial effect of the Film/Viewer Interaction in Apocalypse injections is catholic chant seen within three days and difference apes and hominins? reaches a peak at one to two weeks post-treatment. Catholic. Each treatment lasts approximately three months, following which the procedure can be repeated indefinitely. Sonnet 141. Normally no additional benefit is conferred by catholic, treating more frequently than every three months. At repeat treatment sessions, the sonnet 141 dose may be increased up to chant two-fold if the response from the initial treatment is in Apocalypse Now Essay considered insufficient - usually defined as an effect that does not last longer than two months. However, there appears to catholic be little benefit obtainable from injecting more than 5 Units per site. Sonnet 141. Patients with hemifacial spasm or VII th nerve disorders should be treated as for unilateral blepharospasm, with other affected facial muscles being injected as needed. Electromyographic control may be necessary to identify affected small circumoral muscles. Chant. A 25, 27 or 30 gauge/0.50-0.30 mm needle may be used for superficial muscles, and sonnet 141 a 22 gauge needle may be used for deeper musculature. Catholic. The treatment of cervical dystonia typically may include injection of BOTOX into is Leadership? Essay, the sternocleidomastoid, levator scapulae, scalene, splenius capitis, semispinalis, longissimus and/or the trapezius muscle(s). Chant. This list is not exhaustive as any of the muscles responsible for controlling head position may be involved and therefore require treatment. Interaction. The muscle mass and the degree of catholic chant hypertrophy are factors to be taken into consideration when selecting the bbc bitesize the prelude appropriate dose.

Muscle activation patterns can change spontaneously in chant cervical dystonia without a change in the clinical presentation of NV Future Strategy in Ireland Essay dystonia. In case of chant any difficulty in isolating the individual muscles, injections should be made under electromyographic assistance. Multiple injection sites allow BOTOX to have more uniform contact with the rules of a innervation areas of the dystonic muscle and catholic chant are especially useful in larger muscles. The optimal number of injection sites is Interaction dependent upon the size of the muscle to chant be chemically denervated. Dosing must be tailored to the individual patient based on the patient's head and neck position, location of pain, muscle hypertrophy, patient's body weight, and the prelude patient response. Initial dosing in catholic a naive patient should begin at berlin 1948 the lowest effective dose. To minimise the incidence of catholic dysphagia, the sternomastoid should not be injected bilaterally. Rules. The following doses are recommended: Head rotated toward side of chant shoulder elevation. 50 - 100 Units; at least 2 sites. Holding Internation Strategy In Ireland Essay. 50 Units; 1 - 2 sites. 25 - 50 Units; 1 - 2 sites.

25 - 75 Units; 1 - 3 sites. Catholic Chant. 25 - 100 Units; 1 - 8 sites. Head rotation only. 25 - 100 Units; at Film/Viewer in Apocalypse Now Essay least 2 sites if 25 Units given. Head tilted toward side of shoulder elevation. 25 - 100 Units at catholic chant posterior border; at least 2 sites if 25 Units given. 25 - 100 Units; at least 2 sites. In Addition To Bipedalism, Other Difference Apes. 25 - 75 Units; at least 2 sites. 25 - 100 Units; 1 - 8 sites. Bilateral posterior cervical muscle spasm with elevation of the catholic face.

Splenius capitis and cervicis. 50 - 200 Units; 2 - 8 sites, treat bilaterally. The Prelude. (This is the chant total dose and Film/Viewer in Apocalypse not the catholic dose for each side of the neck) No more than 50 Units should be given at knight any one injection site. Chant. No more than 100 Units should be given to the sternomastoid. No more than 200 Units in total should be injected for Rhandstad Internation Essay the first course of therapy, with adjustments made in subsequent courses dependent on the initial response, up to a maximum total dose of 300 Units. Treatment intervals of less than 10 weeks are not recommended. Chant. Sterile 30 gauge, 0.5 inch needle. A 1 inch needle may be needed in oedipus at colonus the neck region for chant patients with extremely thick neck muscles. In Apocalypse Now Essay. Injections should be divided across 7 specific head/neck muscle areas as specified in the diagrams below. With the catholic exception of the the prelude procerus muscle, which should be injected at chant 1 site (midline), all muscles should be injected bilaterally with half the Expansion in Ireland Essay number of catholic injection sites administered to What the left, and half to the right side of the catholic head and sonnet 141 neck. The following diagrams indicate the catholic injection sites: If there is a predominant pain location(s), additional injections to one or both sides may be administered in up to 3 specific muscle groups (occipitalis, temporalis and trapezius), up to the maximum dose per muscle as indicated in the table below.

The following diagrams indicate recommended muscle groups for optional additional injections: 155 Units to crisis 1948 195 Units administered intramuscularly as 0.1 ml (5 Units) injections to catholic chant 31 and up to oedipus at colonus 39 sites. Total Dosage (number of sites a ) 10 Units (2 sites) 20 Units (4 sites) 40 Units (8 sites) up to 50 Units (up to catholic chant 10 sites) 30 Units (6 sites) up to 40 Units (up to of a 8 sites) Cervical Paraspinal Muscle Group b. 20 Units (4 sites) 30 Units (6 sites) up to 50 Units (up to 10 sites) 155 Units to 195 Units. a 1 IM injection site = 0.1 ml = 5 Units BOTOX. Chant. b Dose distributed bilaterally. What Is The. The recommended re-treatment schedule is catholic every 12 weeks. Knight. The injection needle should be filled (primed) with approximately 1 ml of the reconstituted BOTOX solution prior to the start of the catholic chant injections (depending on oedipus at colonus the needle length) to chant remove any air.

The reconstituted solution of BOTOX (100 Units/10 ml) is injected via a flexible or rigid cystoscope, avoiding the Film/Viewer Interaction trigone and base. The bladder should be instilled with enough saline to catholic achieve adequate visualisation for the injections and avoid backflow of the product, but over-distension should be avoided. Rules Of A Knight. The needle should be inserted approximately 2 mm into the detrusor, and catholic 20 injections of sonnet 141 0.5 ml each (total volume 10 ml) should be spaced approximately 1 cm apart (see figure below). Catholic. For the final injection, approximately 1 ml of sterile unpreserved normal saline (0.9% sodium chloride for injection) should be injected so the full dose is delivered. What Is Leadership?. The recommended dose is 100 Units of catholic BOTOX, as 0.5 ml (5 Units) injections across 20 sites in at colonus the detrusor muscle. For the catholic chant patient preparation and monitoring, see section 4.4. After the injections are given, the saline used for is Leadership? Essay bladder wall visualisation should not be drained so that the patients can demonstrate their ability to void prior to leaving the catholic clinic. The patient should be observed for at What least 30 minutes post-injection and chant until a spontaneous void has occurred. Patients should be considered for reinjection when the oedipus at colonus clinical effect of the previous injection has diminished but no sooner than 3 months from the prior bladder injection. Urinary incontinence due to catholic chant neurogenic detrusor overactivity.

The injection needle should be filled (primed) with approximately 1 ml of the reconstituted BOTOX solution prior to crisis 1948 the start of the injections (depending on the needle length) to remove any air. The reconstituted solution of catholic chant BOTOX (200 Units/30 ml) is injected via a flexible or rigid cystoscope, avoiding the What trigone and chant base. The bladder should be instilled with enough saline to what is the major apes and hominins? achieve adequate visualisation for the injections and catholic chant avoid backflow of the product, but over-distension should be avoided. Sonnet 141. The needle should be inserted approximately 2 mm into catholic chant, the detrusor, and 30 injections of 1 ml each (total volume 30 ml) should be spaced approximately 1 cm apart (see figure above). For the final injection, approximately 1 ml of sterile unpreserved normal saline (0.9% sodium chloride for What is Leadership? Essay injection) should be injected so the chant full dose is What Essay delivered. After the catholic chant injections are given, the the prelude saline used for catholic bladder wall visualisation should be drained.

The recommended dose is sonnet 141 200 Units of BOTOX, as 1 ml ( 6.7 Units) injections across 30 sites in the detrusor muscle. Catholic. For the bbc bitesize patient preparation and monitoring, see section 4.4. Patients should be considered for reinjection when the clinical effect of the catholic previous injection has diminished, but no sooner than 3 months from the prior bladder injection. Limited data are available beyond 2 treatments. No urodynamic data beyond 2 treatments and no histopathological data after repeated treatment are currently available. Patients should not receive multiple treatments in the event of limited symptomatic improvement.

SKIN AND SKIN APPENDAGE DISORDERS: Primary hyperhidrosis of the axillae. Rules Of A. Sterile 30 gauge needle. The hyperhidrotic area to be injected may be defined by using standard staining techniques, e.g. Minor?s iodine-starch test. Chant. 50 Units of BOTOX is injected intradermally to each axilla, evenly distributed in rules multiple sites approximately 1-2 cm apart. The recommended injection volume for intradermal injection is catholic chant 0.1-0.2 ml.

Doses other than 50 Units per axilla cannot be recommended. Clinical improvement generally occurs within the first week after injection and persists for 4-7 months. Repeat injection of knight BOTOX can be administered when the catholic clinical effect of sonnet 141 a previous injection diminishes and the treating physician deems it necessary. Injections should not be repeated more frequently than every 16 weeks. Chant. Glabellar lines seen at bbc bitesize maximum frown. Sterile 30 gauge needle. Before injection, the thumb or index finger is to be placed firmly below the chant orbital rim in sonnet 141 order to catholic prevent extravasation below the orbital rim.

The needle should be oriented superiorly and What is Leadership? Essay medially during the injection. In addition, injections near the catholic chant levator palpebrae superioris muscle must be avoided, particularly in Film/Viewer Interaction in Apocalypse Now Essay patients with larger brow-depressor complexes (depressor supercilii). Injections in catholic the corrugator muscle must be done in in Apocalypse the central part of catholic chant that muscle, a distance of at least 1 cm above the arch of the eyebrows (see figure). Sonnet 141. Care should be taken to ensure that BOTOX is chant not injected into in Apocalypse, a blood vessel when it is catholic injected in the glabellar lines seen at maximum frown, see section 4.4. A volume of 0.1 ml (4 Units) is berlin crisis administered in catholic chant each of the at colonus 5 injection sites (see Figure): 2 injections in each corrugator muscle and catholic chant 1 injection in the procerus muscle for a total dose of bbc bitesize 20 Units. In order to catholic reduce the Rhandstad Essay risk of catholic eyelid ptosis, the is the major and hominins? maximum dose of 4 Units for each injection site as well as the number of injection sites should not be exceeded. Treatment intervals should not be more frequent than every three months.

In the event of treatment failure or diminished effect following repeat injections, alternative treatment methods should be employed. In case of insufficient dose a second treatment session should be initiated by catholic, adjusting the total dose up to 40 or 50 Units, taking into knight, account the catholic analysis of the in addition to bipedalism, what other major difference and hominins? previous treatment failure (see information in chant All indications). The efficacy and rules of a safety of catholic repeat injections of bbc bitesize the prelude BOTOX for the treatment of glabellar lines beyond 12 months has not been evaluated. Catholic. Crow's feet lines seen at maximum smile. Sterile 30 gauge needle. Film/Viewer Now Essay. Injections should be given with the catholic chant needle tip bevel up and bbc bitesize oriented away from the catholic eye. Holding NV Future Internation Expansion Strategy. The first injection (A) should be made approximately 1.5 to catholic chant 2.0 cm temporal to bbc bitesize the prelude the lateral canthus and just temporal to catholic the orbital rim. If the the prelude lines in the crow's feet region are above and catholic chant below the lateral canthus, inject as shown in Figure 1. At Colonus. Alternatively, if the catholic chant lines in sonnet 141 the crow's feet region are primarily below the lateral canthus, inject as shown in Figure 2. In order to catholic chant reduce the 1948 risk of eyelid ptosis, injections should be made temporal to the orbital rim, thereby maintaining a safe distance from the muscle controlling eyelid elevation. Care should be taken to ensure that BOTOX is not injected into chant, a blood vessel when it is injected in the crow's feet lines seen at 1948 maximum smile (see section 4.4). A volume of catholic 0.1 ml (4 Units) is oedipus at colonus administered in each of the chant 3 injection sites per side (total of sonnet 141 6 injection sites) in the lateral orbicularis oculi muscle, for a total dose of catholic 24 Units in a total volume of 0.6 ml (12 Units per oedipus side). For simultaneous treatment with glabellar lines seen at maximum frown, the catholic dose is 24 Units for bbc bitesize crow's feet lines seen at maximum smile and chant 20 Units for glabellar lines (see Administration guidance for glabellar lines) for in Apocalypse Now Essay a total dose of 44 Units in a total volume of 1.1 ml.

In order to catholic reduce the risk of oedipus eyelid ptosis, the maximum dose of catholic chant 4 Units for each injection site as well as the number of Rhandstad Expansion Essay injection sites should not be exceeded. Treatment intervals should not be more frequent than every 3 months. The efficacy and safety of repeat injections of BOTOX for catholic the treatment of rules crow's feet lines beyond 12 months has not been evaluated. In case of catholic chant treatment failure after the first treatment session, i.e. absence, at one month after injection, of crisis significant clinical improvement from baseline, the chant following actions should be taken: - Clinical verification, which may include electromyographic examination in a specialist setting, of the Film/Viewer Interaction in Apocalypse action of the chant toxin on oedipus at colonus the injected muscle(s); - Analysis of the catholic causes of failure, e.g. Crisis. bad selection of catholic chant muscles to is Leadership? be injected, insufficient dose, poor injection technique, appearance of fixed contracture, antagonist muscles too weak, formation of toxin-neutralising antibodies; - Re-evaluation of the catholic appropriateness of treatment with botulinum toxin type A; - In the absence of any undesirable effects secondary to sonnet 141 the first treatment session, instigate a second treatment session as following: i) adjust the chant dose, taking into account the analysis of the earlier treatment failure; ii) use EMG; and iii) maintain a three-month interval between the sonnet 141 two treatment sessions. In the catholic chant event of treatment failure or diminished effect following repeat injections alternative treatment methods should be employed. - known hypersensitivity to What is Leadership? botulinum toxin type A or to any of the excipients listed in section 6.1; - presence of infection at catholic chant the proposed injection site(s). Rules Knight. For the management of chant bladder disorders: - urinary tract infection at the time of treatment; - acute urinary retention at what is the other major between and hominins? the time of treatment, in catholic patients who are not routinely catheterising; - patients who are not willing and/or able to initiate catheterisation post-treatment if required; - presence of rules knight bladder calculi. The recommended dosages and chant frequencies of administration of BOTOX should not be exceeded due to at colonus the potential for overdose, exaggerated muscle weakness, distant spread of toxin and the formation of chant neutralising antibodies. Film/Viewer Interaction In Apocalypse Now Essay. Initial dosing in treatment naive patients should begin with the catholic chant lowest recommended dose for the specific indication. Holding NV Future Internation Expansion Essay. Prescribers and patients should be aware that side effects can occur despite previous injections being well tolerated. Caution should therefore be exercised on chant the occasion of each administration.

Side effects related to spread of What is Leadership? Essay toxin distant from the site of catholic administration have been reported (see section 4.8), sometimes resulting in sonnet 141 death, which in catholic chant some cases was associated with dysphagia, pneumonia and/or significant debility. The symptoms are consistent with the mechanism of action of botulinum toxin and have been reported hours to weeks after injection. The risk of symptoms is probably greatest in is Leadership? Essay patients who have underlying conditions and comorbidities that would predispose them to these symptoms, including children and catholic adults treated for sonnet 141 spasticity, and are treated with high doses. Patients treated with therapeutic doses may also experience exaggerated muscle weakness. Elderly and debilitated patients should be treated with caution. Catholic. Generally, clinical studies of knight BOTOX did not identify differences in catholic chant responses between the elderly and younger patients except for facial lines (see section 5.1). Rhandstad NV Future Internation Expansion In Ireland Essay. Dose selection for catholic an elderly patient should be cautious, usually starting at the low end of the dosing range. Bbc Bitesize. Consideration should be given to the risk-benefit implications for the individual patient before embarking on treatment with BOTOX.

Dysphagia has also been reported following injection to sites other than the chant cervical musculature (see section 4.4 'Cervical Dystonia'). BOTOX should only be used with extreme caution and What is Leadership? under close supervision in patients with subclinical or clinical evidence of defective neuromuscular transmission e.g. Chant. myasthenia gravis or Lambert-Eaton Syndrome in patients with peripheral motor neuropathic diseases (e.g. amyotrophic lateral sclerosis or motor neuropathy) and in to bipedalism, difference between apes and hominins? patients with underlying neurological disorders. Such patients may have an increased sensitivity to agents such as BOTOX, even at therapeutic doses, which may result in excessive muscle weakness and an increased risk of clinically significant systemic effects including severe dysphagia and chant respiratory compromise. The botulinum toxin product should be used under specialist supervision in sonnet 141 these patients and should only be used if the catholic benefit of treatment is considered to outweigh the risk. Patients with a history of dysphagia and aspiration should be treated with extreme caution. Patients or caregivers should be advised to seek immediate medical care if swallowing, speech or respiratory disorders arise. 1948. As with any treatment with the catholic potential to allow previously-sedentary patients to resume activities, the in addition to bipedalism, is the other major apes sedentary patient should be cautioned to chant resume activity gradually. The relevant anatomy, and any alterations to the anatomy due to sonnet 141 prior surgical procedures, must be understood prior to catholic chant administering BOTOX and injection into of a knight, vulnerable anatomic structures must be avoided.

Pneumothorax associated with injection procedure has been reported following the administration of catholic chant BOTOX near the What thorax. Catholic. Caution is crisis 1948 warranted when injecting in proximity to catholic chant the lung (particularly the apices) or other vulnerable anatomic structures. What Is Leadership? Essay. Serious adverse events including fatal outcomes have been reported in catholic chant patients who had received off-label injections of BOTOX directly into the prelude, salivary glands, the oro-lingual-pharyngeal region, oesophagus and catholic chant stomach. Some patients had pre-existing dysphagia or significant debility. Sonnet 141. Serious and/or immediate hypersensitivity reactions have been rarely reported including anaphylaxis, serum sickness, urticaria, soft tissue oedema, and dyspnoea. Some of these reactions have been reported following the use of BOTOX either alone or in chant conjunction with other products associated with similar reactions. Oedipus. If such a reaction occurs further injection of BOTOX should be discontinued and appropriate medical therapy, such as epinephrine, immediately instituted. One case of anaphylaxis has been reported in which the patient died after being injected with BOTOX inappropriately diluted with 5 ml of chant 1% lidocaine. Sonnet 141. As with any injection, procedure-related injury could occur. Catholic Chant. An injection could result in Holding Essay localised infection, pain, inflammation, paraesthesia, hypoaesthesia, tenderness, swelling, erythema, and/or bleeding/bruising.

Needle-related pain and/or anxiety may result in chant vasovagal responses, e.g. Sonnet 141. syncope, hypotension, etc. Caution should be used when BOTOX is used in catholic chant the presence of of a inflammation at catholic the proposed injection site(s) or when excessive weakness or atrophy is present in is the other major and hominins? the target muscle. Caution should also be exercised when BOTOX is used for catholic treatment of Internation Expansion patients with peripheral motor neuropathic diseases (e.g., amyotrophic lateral sclerosis or motor neuropathy). There have been reports of adverse events following administration of chant BOTOX involving the at colonus cardiovascular system, including arrhythmia and catholic chant myocardial infarction, some with fatal outcomes. Some of is Leadership? these patients had risk factors including pre-existing cardiovascular disease. Catholic Chant. New onset or recurrent seizures have been reported, typically in sonnet 141 patients who are predisposed to experiencing these events.

The exact relationship of catholic chant these events to at colonus botulinum toxin injection has not been established. The reports in children were predominantly from cerebral palsy patients treated for spasticity. Formation of neutralising antibodies to botulinum toxin type A may reduce the catholic effectiveness of berlin 1948 BOTOX treatment by catholic, inactivating the biological activity of the toxin. Rhandstad Holding NV Future Internation Expansion Strategy Essay. Results from some studies suggest that BOTOX injections at catholic chant more frequent intervals or at of a higher doses may lead to greater incidence of antibody formation. Chant. When appropriate, the potential for antibody formation may be minimised by injecting with the lowest effective dose given at the longest clinically indicated intervals between injections. Clinical fluctuations during the repeated use of 1948 BOTOX (as with all botulinum toxins) may be a result of different vial reconstitution procedures, injection intervals, muscles injected and slightly differing potency values given by the biological test method used.

The safety and chant efficacy of BOTOX in in addition to bipedalism, what other major between indications other than those described for chant the paediatric population in sonnet 141 section 4.1 has not been established. Chant. Post-marketing reports of at colonus possible distant spread of catholic toxin have been very rarely reported in rules paediatric patients with comorbidities, predominantly with cerebral palsy. In general the catholic dose used in in addition to bipedalism, what is the other major difference apes these cases was in excess of catholic chant that recommended (see section 4.8). There have been rare spontaneous reports of death sometimes associated with aspiration pneumonia in Holding Strategy in Ireland children with severe cerebral palsy after treatment with botulinum toxin, including following off-label use (e.g. neck area). Catholic. Extreme caution should be exercised when treating paediatric patients who have significant neurologic debility, dysphagia, or have a recent history of oedipus aspiration pneumonia or lung disease. Catholic Chant. Treatment in patients with poor underlying health status should be administered only if the knight potential benefit to the individual patient is chant considered to outweigh the What is Leadership? Essay risks. Focal spasticity associated with paediatric cerebral palsy and catholic chant spasticity of the ankle, hand and sonnet 141 wrist in adult post-stroke patients. BOTOX is catholic chant a treatment of sonnet 141 focal spasticity that has only chant, been studied in association with usual standard of care regimens, and sonnet 141 is not intended as a replacement for these treatment modalities. BOTOX is not likely to be effective in improving range of catholic chant motion at oedipus at colonus a joint affected by chant, a fixed contracture.

BOTOX should only be used for the treatment of focal spasticity in adult post-stroke patients if muscle tone reduction is expected to result in improved function (e.g. Rhandstad NV Future Internation Expansion Essay. improvements in gait), or improved symptoms (e.g. Chant. reduction in muscle spasms or pain), and/or to facilitate care. Caution should be exercised when treating adult patients with post - stroke spasticity who may be at Film/Viewer Interaction in Apocalypse Now Essay increased risk of fall. Chant. In clinical studies where patients were treated for 1948 lower limb spasticity (some of catholic whom also received concurrent treatment for upper limb spasticity), the incidence of fall was 7.2% and 4.9% of patients in the BOTOX and placebo groups, respectively. There have been post-marketing reports of death (sometimes associated with aspiration pneumonia) and of possible distant spread of toxin in children with co-morbidities, predominantly cerebral palsy following treatment with botulinum toxin. See warnings under section 4.4, 'Paediatric use'. Reduced blinking following botulinum toxin injection into Rhandstad Holding Expansion Strategy, the orbicularis muscle can lead to corneal exposure, persistent epithelial defect, and corneal ulceration, especially in patients with VII nerve disorders. Careful testing of catholic chant corneal sensation in eyes previously operated upon, avoidance of injection into the lower lid area to Film/Viewer Interaction in Apocalypse avoid ectropion, and vigorous treatment of any epithelial defect should be employed. This may require protective drops, ointment, therapeutic soft contact lenses, or closure of the eye by patching or other means.

Ecchymosis occurs easily in the soft eyelid tissues. This can be minimised by catholic, applying gentle pressure at Film/Viewer the injection site immediately after injection. Chant. Because of the anticholinergic activity of botulinum toxin, caution should be exercised when treating patients at NV Future Internation in Ireland Essay risk for angle closure glaucoma, including patients with anatomically narrow angles. Patients with cervical dystonia should be informed of the possibility of chant experiencing dysphagia which may be very mild, but could be severe. Dysphagia may persist for two to three weeks after injection, but has been reported to Film/Viewer Now Essay last up to five months post-injection. Consequent to the dysphagia there is the potential for aspiration, dyspnoea and chant occasionally the need for tube feeding. In rare cases dysphagia followed by oedipus, aspiration pneumonia and death has been reported. Catholic. Limiting the in addition other major between dose injected into the sternocleidomastoid muscle to less than 100 Units may decrease the catholic chant occurrence of dysphagia. Patients with smaller neck muscle mass, or patients who receive bilateral injections into the sternocleidomastoid muscle, have been reported to be at greater risk of what other between apes and hominins? dysphagia. Dysphagia is attributable to the spread of the toxin to the oesophageal musculature. Catholic Chant. Injections into the levator scapulae may be associated with an What Essay, increased risk of chant upper respiratory infection and dysphagia.

Dysphagia may contribute to in addition to bipedalism, what other difference and hominins? decreased food and water intake resulting in catholic weight loss and dehydration. Sonnet 141. Patients with subclinical dysphagia may be at increased risk of catholic chant experiencing more severe dysphagia following a BOTOX injection. Sonnet 141. No efficacy has been shown for BOTOX in catholic chant the prophylaxis of headaches in patients with episodic migraine (headaches on 15 days per month). Rules. Patient preparation and monitoring. Prophylactic antibiotics should be administered to chant patients with sterile urine or asymptomatic bacteriuria in accordance with local standard practice. The decision to discontinue anti-platelet therapy should be subject to oedipus at colonus local guidance and benefit/risk consideration for the individual patient. Patients on anti-coagulant therapy need to be managed appropriately to decrease the risk of bleeding. Appropriate medical caution should be exercised when performing the cystoscopy. The patient should be observed for at least 30 minutes post-injection. In patients who are not regularly practicing catheterisation, post-void residual urine volume should be assessed within 2 weeks post-treatment and periodically as medically appropriate. Catholic. Patients should be instructed to sonnet 141 contact their physician if they experience difficulties in voiding as catheterisation may be required.

Prior to catholic injection an intravesical instillation of diluted local anaesthetic, with or without sedation, may be used, per local site practice. If a local anaesthetic instillation is performed, the bladder should be drained and what rinsed with sterile saline before the next steps of the injection procedure. Catholic. Urinary incontinence due to the prelude neurogenic detrusor overactivity. BOTOX injection can be performed under general or local anaesthesia with or without sedation. If a local anaesthetic intravesical instillation is catholic performed, the bladder should be drained and rinsed with sterile saline before the next steps of the injection procedure. Autonomic dysreflexia associated with the procedure can occur and greater vigilance is required in patients known to rules of a be at risk. SKIN AND SKIN APPENDAGE DISORDER.

Primary hyperhidrosis of the chant axillae. At Colonus. Medical history and physical examination, along with specific additional investigations as required, should be performed to exclude potential causes of secondary hyperhidrosis (e.g. hyperthyroidism, phaeochromocytoma). This will avoid symptomatic treatment of catholic hyperhidrosis without the diagnosis and/or treatment of difference between apes underlying disease. Chant. Glabellar lines seen at maximum frown and/or crow's feet lines seen at maximum smile. It is mandatory that BOTOX is used for one single patient treatment only during a single session.

The excess of crisis unused product must be disposed of catholic chant as detailed in Rhandstad Holding Expansion Strategy section 6.6. Particular precautions should be taken for product preparation and catholic chant administration as well as for the inactivation and disposal of the remaining unused solution (see section 6.6). The use of BOTOX is not recommended in to bipedalism, is the other major difference between apes and hominins? individuals under 18 years. Chant. There is limited phase 3 clinical data with BOTOX in patients older than 65 years. Care should be taken to ensure that BOTOX is not injected into a blood vessel when it is injected in the glabellar seen at maximum frown or in bbc bitesize the prelude the crow's feet lines seen at catholic chant maximum smile, see section 4.2. What. There is a risk of eyelid ptosis following treatment, refer to Section 4.2 for catholic administration instructions on how to minimise this risk. 1948. Theoretically, the effect of catholic botulinum toxin may be potentiated by aminoglycoside antibiotics or spectinomycin, or other medicinal products that interfere with neuromuscular transmission (e.g. Sonnet 141. neuromuscular blocking agents). Catholic. The effect of administering different botulinum neurotoxin serotypes at to bipedalism, what major between the same time or within several months of each other is chant unknown. Excessive neuromuscular weakness may be exacerbated by administration of another botulinum toxin prior to the resolution of the effects of a previously administered botulinum toxin. Sonnet 141. No interaction studies have been performed.

No interactions of clinical significance have been reported. There are no data available on the concomitant use of anticholinergics with BOTOX injections in the management of catholic chant overactive bladder. There are no adequate data from the use of botulinum toxin type A in pregnant women. Studies in animals have shown reproductive toxicity (see Section 5.3). Holding Internation Strategy In Ireland Essay. The potential risk for catholic chant humans is unknown. BOTOX is not recommended during pregnancy and in women of sonnet 141 childbearing potential not using contraception. Catholic Chant. There is oedipus at colonus no information on whether BOTOX is catholic chant excreted in What Essay human milk.

The use of BOTOX during breast-feeding cannot be recommended. Catholic Chant. There are no adequate data on the effects on fertility from the use of botulinum toxin type A in women of childbearing potential. Knight. Studies in male and female rats have shown fertility reductions (see section 5.3). Catholic. No studies on the effects on rules of a the ability to catholic drive and Essay use machines have been performed. Catholic Chant. However, BOTOX may cause asthenia, muscle weakness, somnolence, dizziness and visual disturbance, which could affect driving and the operation of is Leadership? Essay machinery. In controlled clinical trials adverse events considered by the investigators to chant be related to BOTOX were reported in 35% of the patients with blepharospasm, 28% with cervical dystonia, 17% with paediatric cerebral palsy, 11% with primary hyperhidrosis of the axillae, 16% with focal spasticity of the upper limb associated with stroke, 15% with focal spasticity of the sonnet 141 lower limb associated with stroke, 26% with overactive bladder, and catholic chant 32% with neurogenic detrusor overactivity.

In clinical trials for crisis chronic migraine, the incidence was 26% with the first treatment and chant declined to Rhandstad NV Future Internation Expansion 11% with a second treatment. Catholic Chant. In controlled clinical trials for glabellar lines seen at maximum frown, adverse events considered by the investigators to is Leadership? Essay be related to catholic chant BOTOX were reported in sonnet 141 23% (placebo 19%) of patients. In treatment cycle 1 of the pivotal controlled clinical trials for chant crow's feet lines seen at oedipus at colonus maximum smile, such events were reported in 8% (24 Units for chant crow's feet lines alone) and bbc bitesize 6% (44 Units: 24 Units for catholic chant crow's feet lines administered simultaneously with 20 Units for bbc bitesize glabellar lines) of patients compared to catholic chant 5% for oedipus placebo. Adverse reactions may be related to treatment, injection technique or both. In general, adverse reactions occur within the catholic chant first few days following injection and, while generally transient, may have a duration of several months or, in rare cases, longer. Local muscle weakness represents the expected pharmacological action of botulinum toxin in Internation Expansion Strategy Essay muscle tissue. However, weakness of catholic chant adjacent muscles and/or muscles remote from the site of injection has been reported. Bbc Bitesize The Prelude. As is chant expected for any injection procedure, localised pain, inflammation, paraesthesia, hypoaesthesia, tenderness, swelling/oedema, erythema, localised infection, bleeding and/or bruising have been associated with the injection. What Is The Major Between Apes And Hominins?. Needle-related pain and/or anxiety have resulted in vasovagal responses, including transient symptomatic hypotension and chant syncope.

Fever and flu syndrome have also been reported after injections of botulinum toxin. b) Adverse reactions - frequency by What Essay, indication. Chant. The frequency of adverse reactions reported in the clinical trials is defined as follows: Very Common (#8805; 1/10); Common (#8805;1/100 to 1/10); Uncommon (#8805;1/1,000 to 1/100); Rare (#8805;1/10,000 to 1/1,000); Very Rare (1/10,000). Film/Viewer Interaction Now Essay. Focal spasticity associated with paediatric cerebral palsy. System Organ Class. Infections and infestations. Catholic Chant. Viral infection, ear infection.

Nervous system disorders. Somnolence, gait disturbance, paraesthesia. Skin and subcutaneous tissue disorders. Musculoskeletal and connective tissue disorders. Myalgia, muscular weakness, pain in to bipedalism, what is the major extremity. Renal and urinary disorders. Chant. General disorders and administration site conditions. Sonnet 141. Malaise, injection site pain, asthenia. Injury, poisoning and procedural complications. Focal upper limb spasticity associated with stroke. System Organ Class.

Nervous system disorders. Hypoasthesia, headache, paraesthesia, incoordination, amnesia. Ear and labyrinth disorders. Nausea, oral paraesthesia. Skin and catholic subcutaneous tissue disorders. Dermatitis, pruritus, rash. Musculoskeletal and connective tissue disorders. Pain in extremity, muscle weakness. Sonnet 141. General disorders and administration site conditions.

Injection site pain, pyrexia, influenza-like illness, injection site haemorrhage, injection site irritation. Catholic Chant. Asthenia, pain, injection site hypersensitivity, malaise, peripheral oedema. Some of the uncommon events may be disease related. Focal lower limb spasticity associated with stroke. In Addition What Is The Apes. System Organ Class. Catholic Chant. Skin and 1948 subcutaneous tissue disorders. Catholic Chant. Musculoskeletal and connective tissue disorders. Crisis. Arthralgia, musculoskeletal stiffness.

General disorders and administration site conditions. Catholic Chant. System Organ Class. Berlin Crisis. Nervous system disorders. Dizziness, facial paresis, facial palsy. Catholic Chant. Punctate keratitis, lagophthalmos, dry eye, photophobia, eye irritation, lacrimation increase.

Keratitis, ectropion, diplopia, entropion, visual disturbance, blurred vision. Corneal ulceration, corneal epithelium defect, corneal perforation. Skin and subcutaneous tissue disorders. General disorders and berlin crisis administration site conditions. Catholic. Irritation, face oedema. System Organ Class.

Infections and infestations. Is Leadership?. Rhinitis, upper respiratory infection. Nervous system disorders. Catholic Chant. Dizziness, hypertonia, hypoaesthesia, somnolence, headache. Diplopia, eyelid ptosis. Respiratory, thoracic and mediastinal disorders. To Bipedalism, Is The Other Major Apes. Dry mouth, nausea. Musculoskeletal and connective tissue disorders.

Musculoskeletal stiffness and musculoskeletal soreness. Catholic. General disorders and Rhandstad Essay administration site conditions. Asthenia, influenza-like illness, malaise. System Organ Class. Nervous system disorders. Headache*, migraine*, facial paresis. Skin and subcutaneous tissue disorders.

Musculoskeletal and connective tissue disorders. Neck pain, myalgia, musculoskeletal pain, musculoskeletal stiffness, muscle spasms, muscle tightness, muscular weakness. General disorders and administration site conditions. Injection site pain. Chant. * In placebo-controlled trials, headache and migraine, including serious cases of intractable or worsening of to bipedalism, apes and hominins? headache/migraine, were reported more frequently with BOTOX (9%) than with placebo (6%). Catholic Chant. They typically occurred within the rules of a first month after the injections and their incidence declined with repeated treatments.

System Organ Class. Infections and infestations. Catholic Chant. Urinary tract infection. Renal and urinary disorders. Urinary retention, pollakiuria, leukocyturia. Residual urine volume* *elevated post-void residual urine volume (PVR) not requiring catheterisation. What Is Leadership? Essay. #8224; procedure-related adverse reactions. Chant. In the sonnet 141 phase 3 clinical trials urinary tract infection was reported in 25.5% of catholic patients treated with BOTOX 100 Units and 9.6% of patients treated with placebo. Urinary retention was reported in 5.8% of Film/Viewer in Apocalypse Now Essay patients treated with BOTOX 100 Units and in 0.4% of chant patients treated with placebo. What Is Leadership?. Clean intermittent catheterisation was initiated in catholic chant 6.5% of patients following treatment with BOTOX 100 Units versus 0.4% in the placebo group.

Overall, 42.5% of patients (n = 470) were #8805; 65 years of crisis age and 15.1% (n = 167) were #8805; 75 years of age. Catholic Chant. No overall difference in the safety profile following BOTOX treatment was observed between patients #8805; 65 years compared to patients 65 years in sonnet 141 these studies, with the exception of urinary tract infection where the incidence was higher in elderly patients in both the placebo and BOTOX groups compared to the younger patients. No change was observed in catholic chant the overall safety profile with repeat dosing. At Colonus. Urinary incontinence due to neurogenic detrusor overactivity. System Organ Class.

Infections and infestations. Urinary tract infection a, b , bacteriuria b. Residual urine volume** b. Musculoskeletal and catholic chant connective tissue disorders. Oedipus At Colonus. Muscular weakness#8224; a , muscle spasm a. Renal and catholic chant urinary disorders. Sonnet 141. Urinary retention a, b. Haematuria* a, b , bladder diverticulum a , dysuria* b. General disorders and administration site conditions. Catholic. Fatigue#8224; a , gait disturbance#8224; a. 1948. Injury, poisoning and procedural complications. Autonomic dysreflexia* a , fall#8224; a. Catholic. * procedure-related adverse reactions. Oedipus. ** elevated PVR not requiring catheterisation. Catholic. #8224; only in multiple sclerosis. a Adverse reactions occurring in the pivotal Phase 3 clinical trials. b Adverse reactions occurring in the post-approval study of BOTOX 100U in MS patients not catheterising at baseline. In the phase 3 clinical trials, urinary tract infection was reported in 49% of patients treated with BOTOX 200 Units and in Rhandstad NV Future Internation Essay 36% of catholic patients treated with placebo (in multiple sclerosis patients: 53% vs. 29%, respectively; in at colonus spinal cord injury patients: 45% vs.

42%, respectively). Chant. Urinary retention was reported in 17% of patients treated with BOTOX 200 Units and in 3% of patients treated with placebo (in multiple sclerosis patients: 29% vs. 4%, respectively; in spinal cord injury patients: 5% vs. 1%, respectively). Among patients who were not catheterising at baseline prior to sonnet 141 treatment, catheterisation was initiated in 39% following treatment with BOTOX 200 Units versus 17% on placebo.

The risk of chant urinary retention increased in Film/Viewer in Apocalypse patients older than 65 years. No change in the type and frequency of adverse reactions was observed following 2 treatments. Catholic Chant. In the post-approval study of BOTOX 100 Units in MS patients not catheterising at baseline, no difference on the MS exacerbation annualised rate (i.e. number of What is Leadership? Essay MS exacerbation events per chant patient-year) was observed (BOTOX=0, placebo=0.07). The Prelude. Catheterisation was initiated in chant 15.2% of patients following treatment with BOTOX 100 Units versus 2.6% on placebo (refer to Section 5.1). Berlin. SKIN AND SKIN APPENDAGE DISORDER: Primary hyperhidrosis of the axillae. System Organ Class. Nervous system disorders. Catholic. Skin and subcutaneous tissue disorders. Bbc Bitesize The Prelude. Hyperhidrosis (non axillary sweating), abnormal skin odour, pruritus, subcutaneous nodule, alopecia. Musculoskeletal and connective tissue disorders.

Pain in extremity. Muscular weakness, myalgia, arthropathy. General disorders and administration site conditions. Catholic. Injection site pain. Pain, injection site oedema, injection site haemorrhage, injection site hypersensitivity, injection site irritation, asthenia, injection site reactions.

Increase in at colonus non axillary sweating was reported in catholic chant 4.5% of sonnet 141 patients within 1 month after injection and showed no pattern with respect to chant anatomical sites affected. What Other Difference Between. Resolution was seen in chant approximately 30% of the bbc bitesize the prelude patients within four months. Weakness of the catholic arm has been also reported uncommonly (0.7%) and sonnet 141 was mild, transient, did not require treatment and chant recovered without sequelae. What Major. This adverse event may be related to treatment, injection technique, or both. In the uncommon event of muscle weakness being reported a neurological examination may be considered. Catholic Chant. In addition, a re-evaluation of injection technique prior to in addition to bipedalism, what is the other difference apes and hominins? subsequent injection is advisable to catholic ensure intradermal placement of Rhandstad Holding Strategy in Ireland injections. In an uncontrolled safety study of BOTOX (50 Units per axilla) in paediatric patients 12 to 17 years of chant age (n= 144), adverse reactions occurring in is Leadership? Essay more than a single patient (2 patients each) comprised injection site pain and hyperhidrosis (non-axillary sweating).

System Organ Class. Infections and infestations. Nervous system disorders. Blepharitis, eye pain, visual disturbance. Catholic Chant. Nausea, oral dryness. Sonnet 141. Skin and chant subcutaneous tissue disorders. Of A Knight. Skin tightness, oedema (face, eyelid, periorbital), photosensitivity reaction, pruritus, dry skin. Musculoskeletal and connective tissue disorders. Chant. Localised muscle weakness. Bbc Bitesize. General disorders and administration site conditions. Catholic. Flu syndrome, asthenia, fever.

The following adverse drug reactions were reported in Film/Viewer Interaction in Apocalypse the double-blind, placebo-controlled clinical studies following injection of catholic chant BOTOX 24 Units for berlin crow's feet lines alone: System Organ Class. Catholic. General disorders and berlin crisis administration site conditions. Injection site haemorrhage*, injection site haematoma* Injection site pain*, injection site paraesthesia. *procedure-related adverse reactions. Crow's feet lines and glabellar lines. The following adverse drug reactions were reported in double-blind, placebo-controlled clinical studies following injection of catholic BOTOX 44 Units (simultaneous treatment of bbc bitesize crow's feet lines and glabellar lines): System Organ Class. General disorders and administration site conditions. Injection site haematoma* Injection site haemorrhage*, injection site pain* *procedure-related adverse reactions. No change was observed in chant the overall safety profile following repeat dosing. NV Future Strategy. c) Additional information. The following list includes adverse drug reactions or other medically relevant adverse events that have been reported since the drug has been marketed, regardless of catholic chant indication, and sonnet 141 may be in addition to chant those cited in section 4.4 (Special warnings and precautions for rules use), and section 4.8 (Undesirable effects). System Organ Class.

Immune system disorders. Catholic Chant. Anaphylaxis, angioedema, serum sickness, urticaria. Berlin. Metabolism and nutrition disorders. Nervous system disorders. Brachial plexopathy, dysphonia, dysarthria, facial paresis, hypoaesthesia, muscle weakness, myasthenia gravis, peripheral neuropathy, paraesthesia, radiculopathy, seizures, syncope, facial palsy. Angle-closure glaucoma (for treatment of catholic blepharospasm), lagophthalmos, strabismus, blurred vision, visual disturbance. Ear and labyrinth disorders. Hypoacusis, tinnitus, vertigo.

Arrhythmia, myocardial infarction. Holding NV Future Internation Strategy In Ireland Essay. Respiratory, thoracic and chant mediastinal disorders. Aspiration pneumonia (some with fatal outcome), dyspnoea, respiratory depression, respiratory failure. Holding NV Future Internation Expansion Strategy Essay. Abdominal pain, diarrhoea, constipation, dry mouth, dysphagia, nausea, vomiting. Skin and catholic chant subcutaneous tissue disorders. Knight. Alopecia, dermatitis psoriasiform, erythema multiforme, hyperhidrosis, madarosis, pruritus, rash.

Musculoskeletal and connective tissue disorders. Muscle atrophy, myalgia. General disorders and administration site conditions. Denervation atrophy, malaise, pyrexia. Reporting of suspected adverse reactions. Reporting suspected adverse reactions after authorisation of the catholic medicinal product is important. It allows continued monitoring of the at colonus benefit/risk balance of the catholic chant medicinal product. Rhandstad Internation Expansion In Ireland. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard. Overdose of BOTOX is a relative term and catholic depends upon dose, site of injection, and underlying tissue properties.

No cases of crisis 1948 systemic toxicity resulting from catholic chant, accidental injection of BOTOX have been observed. The Prelude. Excessive doses may produce local, or distant, generalised and chant profound neuromuscular paralysis. No cases of ingestion of BOTOX have been reported. Signs and What is Leadership? Essay symptoms of overdose are not apparent immediately post-injection. Should accidental injection or ingestion occur or overdose be suspected, the patient should be medically monitored for up to several weeks for catholic chant progressive signs and bbc bitesize symptoms of catholic muscular weakness, which could be local or distant from the site of sonnet 141 injection and chant may include ptosis, diplopia, dysphagia, dysarthria, generalised weakness or respiratory failure. These patients should be considered for further medical evaluation and appropriate medical therapy immediately instituted, which may include hospitalisation.

If the musculature of the oropharynx and sonnet 141 oesophagus are affected, aspiration may occur which may lead to catholic development of at colonus aspiration pneumonia. If the respiratory muscles become paralysed or sufficiently weakened, intubation and assisted respiration will be required until recovery takes place and catholic chant may involve the need for a tracheostomy and 1948 prolonged mechanical ventilation, in addition to other general supportive care. Catholic Chant. ATC class M03A X01 and ATC class D11AX . Bbc Bitesize The Prelude. The active constituent in catholic BOTOX is a protein complex derived from Clostridium botulinum . The protein consists of type A neurotoxin and rules knight several other proteins. Under physiological conditions it is presumed that the complex dissociates and catholic releases the the prelude pure neurotoxin. Clostridium botulinum toxin type A neurotoxin complex blocks peripheral acetyl choline release at presynaptic cholinergic nerve terminals.

Intramuscular injection of the catholic neurotoxin complex blocks cholinergic transport at the neuromuscular junction by oedipus, preventing the release of catholic chant acetylcholine. Bbc Bitesize. The nerve endings of the neuromuscular junction no longer respond to nerve impulses and secretion of the chemotransmitter is prevented (chemical denervation). Re-establishment of catholic chant impulse transmission is by newly formed nerve endings and motor end plates. Clinical evidence suggests that BOTOX reduces pain and neurogenic inflammation and elevates cutaneous heat pain thresholds in a capsaicin induced trigeminal sensitization model. Rhandstad Holding In Ireland Essay. Recovery after intramuscular injection takes place normally within 12 weeks of chant injection as nerve terminals sprout and sonnet 141 reconnect with the endplates. Catholic. After intradermal injection, where the in addition what other between apes target is the chant eccrine sweat glands, the effect lasted for about 4-7 months in bbc bitesize patients treated with 50 Units per axilla. Catholic. There is limited clinical trial experience of the Holding NV Future Expansion in Ireland Essay use of BOTOX in primary axillary hyperhidrosis in catholic chant adolescents between the bbc bitesize the prelude ages of 12 and 18. Catholic Chant. A single, year long, uncontrolled, repeat dose, safety study was conducted in US paediatric patients 12 to sonnet 141 17 years of catholic chant age (N=144) with severe primary hyperhidrosis of the axillae. Participants were primarily female (86.1%) and in addition is the other between Caucasian (82.6%).

Participants were treated with a dose of 50 Units per axilla for a total dose of 100 Units per patient per catholic chant treatment. In Addition To Bipedalism, Other Major And Hominins?. However, no dose finding studies have been conducted in adolescents so no recommendation on catholic posology can be made. Sonnet 141. Efficacy and catholic safety of the prelude BOTOX in this group have not been established. Catholic Chant. BOTOX blocks the Internation Strategy in Ireland release of catholic chant neurotransmitters associated with the genesis of Film/Viewer in Apocalypse pain. The presumed mechanism for headache prophylaxis is by blocking peripheral signals to catholic the central nervous system, which inhibits central sensitisation, as suggested by pre-clinical and clinical pharmacodynamic studies. Following intradetrusor injection, BOTOX affects the efferent pathways of detrusor activity via inhibition of acetylcholine release. Rules. In addition BOTOX inhibits afferent neurotransmitters and sensory pathways.

Clinical efficacy and safety. Catholic Chant. Focal upper limb spasticity associated with stroke. Rhandstad Holding NV Future Internation Strategy Essay. In controlled and open, non-controlled studies, doses between 200 and 240 Units in wrist and flexor muscles were divided among the selected muscles at a given treatment session. Catholic Chant. In controlled studies, improvement in muscle tone occurred within two weeks with the peak effect generally seen within four to oedipus six weeks. In an open, non-controlled continuation study, most patients were re-injected after an interval of 12 to catholic chant 16 weeks, when the effect on muscle tone had diminished. In Addition What Major Between. These patients received up to four injections with a maximal cumulative dose of 960 Units over catholic chant 54 weeks. Focal lower limb spasticity associated with stroke. A double-blind, placebo-controlled, randomised, multi-centre, phase 3 clinical study was conducted in adult post-stroke patients with lower limb spasticity affecting the ankle.

A total of 120 patients were randomised to the prelude receive either BOTOX (n=58; total dose of catholic 300 Units) or placebo (n=62). Rhandstad Internation Expansion Strategy. Significant improvement compared to placebo was observed in the primary endpoint for the overall change from baseline up to week 12 in Modified Ashworth Scale (MAS) ankle score, which was calculated using the catholic area under the curve (AUC) approach. Significant improvements compared to sonnet 141 placebo were also observed for the mean change from chant, baseline in the prelude MAS ankle score at individual post-treatment visits at weeks 4, 6 and 8. The proportion of chant responders (patients with at least a 1 - grade improvement) was also significantly higher (67% - 68%) than in sonnet 141 placebo - treated patients (31% - 36%) at these visits. BOTOX treatment was also associated with significant improvement in the investigator's clinical global impression (CGI) of chant functional disability compared to oedipus at colonus placebo although the catholic chant difference was not significant for the patient's CGI. In initial controlled clinical trials to establish safety and efficacy for cervical dystonia, doses of reconstituted BOTOX ranged from 140 to 280 Units.

In more recent studies, doses ranged from what major between, 95 to chant 360 Units (with an approximate mean of 240 Units). Rules Knight. Clinical improvement generally occurs within the first two weeks after injection. Catholic. The maximum clinical benefit generally occurs by oedipus, six weeks post-injection. The duration of catholic beneficial effect reported in clinical studies showed substantial variation (from 2 to in Apocalypse Now Essay 33 weeks) with a typical duration of approximately 12 weeks. Chronic migraine patients without any concurrent headache prophylaxis who, during a 28-day baseline, had at least 4 episodes and catholic chant #8805; 15 headache days (with at Rhandstad NV Future in Ireland least 4 hours of continuous headache) with at catholic chant least 50% being migraine/probable migraine, were studied in two Phase 3 clinical trials. Patients were allowed to use acute headache treatments and 66% overused acute treatments during the baseline period. During the double-blind phase of the trials, the the prelude main results achieved after two BOTOX treatments administered at catholic a 12-week interval are shown in the table below. Mean change from baseline at Week 24.

Frequency of headache days. Frequency of in addition to bipedalism, other difference apes and hominins? moderate/severe headache days. Frequency of migraine/probable migraine days. Catholic. % patients with 50% reduction in headache days. Total cumulative hours of NV Future Internation Expansion Strategy Essay headache on catholic chant headache days. Frequency of headache episodes. Total HIT-6* scores. * Headache Impact Test. The treatment effect appeared smaller in Holding NV Future Expansion Strategy in Ireland Essay the subgroup of male patients (n=188) than in the whole study population. Chant. Two double-blind, placebo-controlled, randomised, 24-week phase 3 clinical studies were conducted in patients with overactive bladder with symptoms of urge urinary incontinence, urgency, and is Leadership? frequency. A total of catholic chant 1105 patients (mean age of 60 years), whose symptoms had not been adequately managed with at Now Essay least one anticholinergic therapy (inadequate response or intolerable side effects), were randomised to catholic receive either 100 Units of NV Future Strategy Essay BOTOX (n=557), or placebo (n=548), after having discontinued anticholinergics for catholic more than one week. Primary and Secondary Endpoints at oedipus Baseline and Change from catholic chant, Baseline in oedipus at colonus Pooled Pivotal Studies: Daily Frequency of Urinary Incontinence Episodes.

Mean Change #8224; at Week 2. Catholic Chant. Mean Change #8224; at sonnet 141 Week 6. Mean Change #8224; at catholic Week 12 a. Proportion with Positive Treatment Response using Treatment Benefit Scale (%) Daily Frequency of Micturition Episodes. Mean Change #8224; at Week 12 b. Is Leadership?. Daily Frequency of Urgency Episodes. Catholic. Mean Change #8224; at Rhandstad Holding NV Future Strategy in Ireland Week 12 b. Catholic Chant. Incontinence Quality of Life Total Score. Film/Viewer Now Essay. Mean Change #8224; at catholic chant Week 12 bc. Oedipus At Colonus. King's Health Questionnaire: Role Limitation. Catholic Chant. Mean Change #8224; at Essay Week 12 bc. King's Health Questionnaire: Social Limitation. Catholic. Mean Change #8224; at is Leadership? Essay Week 12 bc. Percentage of patients achieving full continence at Week 12 (dry patients over a 3-day diary) Percentage of patients achieving reduction from chant, baseline in urinary incontinence episodes at Week 12. #8224; Least Squares (LS) mean changes are presented. Bbc Bitesize The Prelude. a Co-primary endpoints. Chant. b Secondary endpoints. Rules. c Pre-defined minimally important change from baseline was +10 points for I-QOL and -5 points for KHQ. The median duration of response following BOTOX treatment, based on chant patient request for re-treatment, was 166 days ( 24 weeks).

The median duration of in addition other apes and hominins? response, based on catholic chant patient request for Essay re-treatment, in patients who continued into catholic chant, the open label extension study and oedipus received treatments with only catholic, BOTOX 100 Units (N=438), was 212 days ( A total of 839 patients were evaluated in Film/Viewer Now Essay a long-term open-label extension study. Catholic Chant. For all efficacy endpoints, patients experienced consistent response with re-treatments. The mean reductions from sonnet 141, baseline in daily frequency of urinary incontinence were -3.07 (n=341), -3.49 (n=292), and -3.49 (n=204) episodes at catholic week 12 after the of a knight first, second, and catholic third BOTOX 100 Unit treatments, respectively. The corresponding proportions of in addition to bipedalism, what is the other major between apes patients with a positive treatment response on the Treatment Benefit Scale were 63.6% (n=346), 76.9% (n=295), and 77.3% (n=207), respectively. In the catholic pivotal studies, none of the bbc bitesize the prelude 615 patients with analysed serum specimens developed neutralising antibodies after 1 3 treatments. In patients with analysed specimens from the catholic pivotal phase 3 and berlin the open-label extension studies, neutralising antibodies developed in catholic chant 0 of 954 patients (0.0%) while receiving BOTOX 100 Unit doses and sonnet 141 3 of 260 patients (1.2%) after subsequently receiving at catholic chant least one 150 Unit dose. One of crisis 1948 these three patients continued to experience clinical benefit. Compared to catholic chant the overall BOTOX treated population, patients who developed neutralising antibodies generally had shorter duration of response and is Leadership? consequently received treatments more frequently (see section 4.4). Urinary incontinence due to neurogenic detrusor overactivity.

Pivotal Phase 3 Clinical Trials. Two double-blind, placebo-controlled, randomised phase 3 clinical studies were conducted in a total of 691 patients with spinal cord injury or multiple sclerosis, who were not adequately managed with at least one anticholinergic agent and catholic chant were either spontaneously voiding or using catheterisation. These patients were randomised to receive either 200 Units of BOTOX (n=227), 300 Units of BOTOX (n=223), or placebo (n=241). Is Leadership? Essay. Primary and catholic chant Secondary Endpoints at Baseline and in addition what is the other difference apes and hominins? Change from Baseline in Pooled Pivotal Studies: Weekly Frequency of chant Urinary Incontinence. Mean Change #8224; at Week 2. The Prelude. Mean Change #8224; at Week 6 a. Mean Change #8224; at catholic Week 12. In Addition Is The Other Major Difference Between And Hominins?. Maximum Cystometric Capacity (ml) Mean Change #8224; at catholic chant Week 6 b. Maximum Detrusor Pressure during 1st Involuntary Detrusor Contraction (cmH20) Mean Change #8224; at Week 6 b. Incontinence Quality of NV Future Expansion Strategy in Ireland Life Total Score c,d. Mean Change #8224; at Week 6 b. Catholic. Mean Change #8224; at Essay Week 12.

Percentage of patients achieving full continence at Week 6 (dry patients over a 7 day diary) Percentage of patients achieving reduction from baseline in urinary incontinence episodes at Week 6. #8224; LS mean changes are presented. a Primary endpoint. b Secondary endpoints. c I-QOL total score scale ranges from 0 (maximum problem) to catholic 100 (no problem at all). d In the pivotal studies, the pre-specified minimally important difference (MID) for I-QOL total score was 8 points based on MID estimates of in addition major difference between 4-11 points reported in catholic neurogenic detrusor overactivity patients. Berlin Crisis. The median duration of response, based on time to qualification for catholic re-treatment (time to 50% reduction in Rhandstad Holding Essay incontinence episodes), was 42 weeks in chant the 200 Unit dose group. NV Future Expansion Strategy. The median interval between the first and second administrations was 42 weeks in patients with spinal cord injury and catholic 45 weeks in in addition to bipedalism, difference between apes patients with multiple sclerosis. Catholic Chant. The median duration of response, based on time to Interaction Now Essay qualification for catholic re-treatment (at least 1 urinary incontinence episode in a 3 day diary), in patients who continued into the open label extension study and received treatments with only Film/Viewer, BOTOX 200 Units (N=174), was 264 days ( For all efficacy endpoints in the pivotal phase 3 studies, patients experienced consistent response with re-treatment (n=116). None of the 475 patients with analysed serum specimens developed neutralising antibodies after 1-2 treatments.

In patients with analysed specimens in chant the drug development program (including the 1948 open-label extension study), neutralising antibodies developed in 3 of 300 patients (1.0%) after receiving only BOTOX 200 Unit doses and catholic 5 of of a knight 258 patients (1.9%) after receiving at least one 300 Unit dose. Four of these eight patients continued to chant experience clinical benefit. Compared to the overall BOTOX treated population, patients who developed neutralising antibodies generally had shorter duration of response and consequently received treatments more frequently (see section 4.4). In the of a knight multiple sclerosis (MS) patients enrolled in catholic chant the pivotal studies, the MS exacerbation annualised rate (i.e. Of A Knight. number of chant MS exacerbation events per patient year) was 0.23 in oedipus at colonus the 200 Unit dose group and chant 0.20 in Film/Viewer Interaction in Apocalypse Now Essay the placebo group. With repeated BOTOX treatments, including data from a long term study, the MS exacerbation annualised rate was 0.19 during each of the first two BOTOX treatment cycles.

A placebo controlled, double-blind post-approval study was conducted in multiple sclerosis (MS) patients with urinary incontinence due to catholic chant neurogenic detrusor overactivity who were not adequately managed with at Rhandstad Holding Expansion least one anticholinergic agent and catholic not catheterising at knight baseline. These patients were randomised to catholic chant receive either 100 Units of BOTOX (n=66) or placebo (n=78). Rules. Significant improvements compared to chant placebo in bbc bitesize the primary efficacy variable of change from baseline in daily frequency of incontinence episodes were observed for chant BOTOX (100 Units) at the primary efficacy time point at oedipus week 6, including the percentage of dry patients. Significant improvements in catholic chant urodynamic parameters, and Incontinence Quality of Life questionnaire (I-QOL), including avoidance limiting behaviour, psychosocial impact and social embarrassment were also observed. Results from the post-approval study are presented below: Primary and Secondary Endpoints at Film/Viewer Baseline and Change from Baseline in catholic chant Post-Approval Study of BOTOX 100 Units in MS patients not catheterising at baseline: Daily Frequency of Urinary Incontinence* Mean Change at Week 2. Mean Change at oedipus Week 6 a. Mean Change at catholic chant Week 12. Maximum Cystometric Capacity (mL) Mean Change at Week 6 b. Maximum Detrusor Pressure during 1 st Involuntary Detrusor Contraction.

Mean Change at sonnet 141 Week 6 b. Incontinence Quality of Life Total Score c,d. Catholic Chant. Mean Change at Week 6 b. Mean Change at Week 12. * Percentage of dry patients (without incontinence) throughout week 6 was 53.0% (100 Unit BOTOX group) and bbc bitesize 10.3% (placebo) a Primary endpoint. b Secondary endpoints. Catholic Chant. c I-QOL total score scale ranges from rules, 0 (maximum problem) to 100 (no problem at all). d The pre-specified minimally important difference (MID) for chant I-QOL total score was 11 points based on rules MID estimates of 4-11 points reported in catholic neurogenic detrusor overactivity patients. What Is The Other Difference Apes. The median duration of response in this study, based on patient request for re-treatment, was 362 days ( 52 weeks) for chant BOTOX 100 Unit dose group compared to rules 88 days ( 13 weeks) with placebo. SKIN AND SKIN APPENDAGE DISORDER. 537 patients with moderate to severe glabellar lines between the catholic eyebrows seen at maximum frown have been included in clinical studies. BOTOX injections significantly reduced the severity of bbc bitesize the prelude glabellar lines seen at maximum frown for up to catholic 4 months, as measured by in addition is the other difference between, the investigator assessment of glabellar line severity at catholic maximum frown and by to bipedalism, what is the other major between, subject's global assessment of change in catholic chant appearance of berlin crisis 1948 his/her glabellar lines seen at chant maximum frown.

Improvement generally occurred within one week of treatment. Sonnet 141. None of the clinical endpoints included an objective evaluation of the catholic psychological impact. At Colonus. Thirty days after injection, 80% (325/405) of chant BOTOX-treated patients were considered by investigators as treatment responders (none or mild severity at maximum frown), compared to 3% (4/132) of placebo-treated patients. At this same timepoint, 89% (362/405) of BOTOX-treated patients felt they had a moderate or better improvement, compared to Essay 7% (9/132) of catholic placebo-treated patients. Oedipus. BOTOX injections also significantly reduced the chant severity of oedipus at colonus glabellar lines at rest. Of the catholic 537 patients enrolled, 39% (210/537) had moderate to bbc bitesize severe glabellar lines at catholic chant rest (15% had no lines at Film/Viewer in Apocalypse Now Essay rest). Catholic Chant. Of these, 74% (119/161) of BOTOX-treated patients were considered treatment responders (none or mild severity) thirty days after injection, compared with 20% (10/49) of placebo-treated patients. There is limited phase 3 clinical data with BOTOX in patients older than 65 years. Only 6.0% (32/537) of Interaction in Apocalypse subjects were 65 years old and efficacy results obtained were lower in this population.

1362 patients with moderate to severe crow's feet lines seen at maximum smile, either alone (n=445, Study 191622-098) or also with moderate to severe glabellar lines seen at maximum frown (n=917, Study 191622-099), were enrolled. BOTOX injections significantly reduced the severity of crow's feet lines seen at maximum smile compared to placebo at all timepoints (p 0.001) for up to 5 months (median 4 months). Catholic Chant. Improvement assessed by is Leadership?, the investigator occurred within one week of treatment. This was measured by the proportion of patients achieving a crow's feet lines severity rating of catholic chant none or mild at maximum smile in both pivotal studies; until day 150 (end of bbc bitesize study) in Study 191622-098 and day 120 (end of first treatment cycle) in Study 191622-099. Chant. For both investigator and crisis 1948 subject assessments, the proportion of chant subjects achieving none or mild crow's feet lines severity seen at maximum smile was greater in patients with moderate crow's feet lines seen at maximum smile at sonnet 141 baseline, compared to patients with severe crow's feet lines seen at catholic chant maximum smile at of a knight baseline. Table 1 summarises results at day 30, the timepoint of the primary efficacy endpoint.

In Study 191622-104 (extension to Study 191622-099), 101 patients previously randomised to placebo were enrolled to chant receive their first treatment at the 44 Units dose. Sonnet 141. Patients treated with BOTOX had a statistically significant benefit in catholic the primary efficacy endpoint compared to placebo at day 30 following their first active treatment. Sonnet 141. The response rate was similar to the 44 Units group at chant day 30 following first treatment in Study 191622-099. What Essay. A total of catholic 123 patients received 4 cycles of in addition to bipedalism, is the major difference 44 Units BOTOX for combined crow's feet and catholic glabellar lines treatment. The Prelude. Day 30: Investigator and Patient Assessment of Crow's Feet Lines Seen at Maximum Smile - Responder Rates (% of catholic Patients Achieving Crow's Feet Lines Severity Rating of knight None or Mild) (crow's feet lines) (crow's feet lines) (24 Units crow's feet lines; 20 Units glabellar lines) *p 0.001 (BOTOX vs placebo) Improvements from catholic chant, baseline in Holding NV Future Expansion Strategy in Ireland Essay subject-assessment of the appearance of crow's feet lines seen at maximum smile were seen for chant BOTOX (24 Units and 1948 44 Units) compared to placebo, at chant day 30 and at bbc bitesize the prelude all timepoints following each treatment cycle in both pivotal studies (p0.001).

Treatment with BOTOX 24 Units also significantly reduced the chant severity of crow's feet lines at to bipedalism, what is the major difference rest. Catholic Chant. Of the 528 patients treated, 63% (330/528) had moderate to severe crow's feet lines at rest at sonnet 141 baseline. Catholic Chant. Of these, 58% (192/330) of rules BOTOX-treated patients were considered treatment responders (none or mild severity) thirty days after injection, compared with 11% (39/352) of chant placebo-treated patients. Improvements in subject's self-assessment of What age and attractiveness were also seen for BOTOX (24 Units and chant 44 Units) compared to placebo using the Facial Line Outcomes (FLO-11) questionnaire, at is the other between apes the primary timepoint of day 30 (p0.001) and at catholic all subsequent timepoints in rules of a both pivotal studies. In the chant pivotal studies, 3.9% (53/1362) of Holding Strategy patients were older than 65 years of age. Patients in this age group had a treatment response as assessed by the investigator, of 36% (at day 30) for BOTOX (24 Units and 44 Units).When analysed by catholic, age groups of sonnet 141 #8804;50 years and chant 50 years, both populations demonstrated statistically significant improvements compared to oedipus placebo. Treatment response for catholic BOTOX 24 Units, as assessed by rules knight, the investigator, was lower in the group of subjects 50 years of catholic chant age than those #8804;50 years of age (42.0% and berlin 1948 71.2%, respectively). Overall BOTOX treatment response for catholic crow's feet lines seen at maximum smile is rules lower (60%) than that observed with treatment for glabellar lines seen at maximum frown (80%).

916 patients (517 patients at 24 Units and 399 patients at 44 Units) treated with BOTOX had specimens analysed for antibody formation. Catholic. No patients developed the presence of oedipus at colonus neutralising antibodies. a) General characteristics of the active substance: Classical absorption, distribution, biotransformation and catholic chant elimination studies on the active substance have not been performed due to the extreme toxicity of in addition to bipedalism, what is the other between apes and hominins? botulinum toxin type A. Catholic. b) Characteristics in patients: Human ADME studies have not been performed due to the nature of the of a knight product. Catholic. It is bbc bitesize believed that little systemic distribution of chant therapeutic doses of bbc bitesize the prelude BOTOX occurs. BOTOX is probably metabolised by proteases and the molecular components recycled through normal metabolic pathways. Non-clinical data based on conventional studies of safety pharmacology, repeated dose toxicity and catholic genotoxicity reveal no special hazard for Essay humans other than exaggerated pharmacological effects predictable at chant high doses, given the neurotoxic nature of oedipus BOTOX. Carcinogenicity studies have not been conducted.

In monkeys receiving a single intramuscular (i.m.) injection of catholic chant BOTOX, the No Observed Effect Level (NOEL) ranged from rules knight, 4 to catholic 24 Units/kg. The i.m. LD 50 was reported to be 39 Units/kg. Toxicity on repeated injection. In three different studies (six months in rats; 20 weeks in Rhandstad Holding Internation Essay juvenile monkeys; 1 year in catholic chant monkeys) where the animals received i.m. Bbc Bitesize The Prelude. injections, the chant NOEL was at the following respective BOTOX dosage levels: 4 Units/kg, 8 Units/kg and 4 Units/kg. The main systemic effect was a transient decrease in body weight gain. There was no indication of a cumulative effect in the animal studies when BOTOX was given at dosage intervals of 1 month or greater. Decrease in Holding NV Future Internation Expansion Strategy Essay bodyweight was observed following a single intradetrusor injection of 10 Units/kg BOTOX in rats. To simulate inadvertent injection, a single dose of catholic chant BOTOX ( 7 Units/kg) was administered into the prostatic urethra and proximal rectum, the seminal vesicle and urinary bladder wall, or the sonnet 141 uterus of monkeys ( 3 Units/kg) without adverse clinical effects. However, bladder stones have been observed in catholic chant monkeys given a single dose of BOTOX to the prostatic urethra and proximal rectum, and in a repeated dose intraprostatic study.

Due to anatomical differences the clinical relevance of these findings is NV Future Internation Expansion unknown. In a 9 month repeat dose intradetrusor study (4 injections), eyelid ptosis was observed at catholic chant 24 Units/kg, and mortality was observed at doses #8805;24 Units/kg. No adverse effects were observed in monkeys at the prelude 12 Units/kg, which corresponds to a 3-fold greater exposure than the catholic chant recommended clinical dose of berlin crisis 1948 200 Units for catholic urinary incontinence due to neurogenic detrusor overactivity (based on a 50 kg person). BOTOX was shown not to cause ocular or dermal irritation, or give rise to toxicity when injected into bbc bitesize the prelude, the vitreous body in rabbits. Catholic. Allergic or inflammatory reactions in the area of the sonnet 141 injection sites are rarely observed after BOTOX administration. However, formation of chant haematoma may occur.

When pregnant mice and rats were injected intramuscularly during the in addition is the other major apes and hominins? period of organogenesis, the developmental NOEL of catholic BOTOX was at 4 Units/kg. Reductions in ossification were observed at 8 and 16 Units/kg (mice) and reduced ossification of the hyoid bone at the prelude 16 Units/kg (rats). Reduced foetal body weights were observed at 8 and chant 16 Units/kg (rats). In a range-finding study in in addition what is the rabbits, daily injections at catholic chant dosages of Strategy Essay 0.5 Units/kg/day (days 6 to chant 18 of gestation), and 4 and Rhandstad Holding Expansion Strategy in Ireland Essay 6 Units/kg (administered on days 6 and catholic chant 13 of gestation), caused death and sonnet 141 abortions among surviving dams. External malformations were observed in one foetus each in the 0.125 Units/kg/day and chant the 2 Units/kg dosage groups. The rabbit appears to be a very sensitive species to oedipus BOTOX treatment. Chant. Impairment of fertility and reproduction. The reproductive NOEL following i.m. injection of crisis 1948 BOTOX was 4 Units/kg in catholic chant male rats and sonnet 141 8 Units/kg in female rats. Higher dosages were associated with dose-dependent reductions in chant fertility. Provided impregnation occurred, there were no adverse effects on What Essay the numbers or viability of the catholic chant embryos sired or conceived by treated male or female rats.

Pre- and post-natal developmental effects. In Addition To Bipedalism, Is The Major Difference Between Apes. In female rats, the chant reproductive NOEL was 16 Units/kg. The developmental NOEL was 4 Units/kg. BOTOX showed antigenicity in mice only in at colonus the presence of catholic adjuvant. BOTOX was found to What is Leadership? be slightly antigenic in chant the guinea pig. No haemolysis was detected up to rules of a 100 Units/ml of chant BOTOX in normal human blood. At Colonus. In the chant absence of Interaction Now Essay compatibility studies, this medicinal product should not be mixed with other medicinal products. After reconstitution, stability has been demonstrated for 24 hours at 2°C 8°C. From a microbiological point of view, the product should be used immediately.

If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2°C to 8°C (see also section 6.6). Store in a refrigerator (2°C-8°C), or store in a freezer (at or below -5°C). For storage conditions of the catholic chant reconstituted medicinal product see section 6.3. Clear glass vial, with rubber stopper and tamper-proof aluminium seal, containing white powder for solution for injection. Of A Knight. #8226; Carton comprising one 100 Allergan Unit vial and catholic package leaflet. Oedipus. #8226; Packs containing one, two, three or six cartons. Not all pack sizes may be marketed. Catholic Chant. BOTOX is what is the other between apes and hominins? reconstituted prior to catholic use with sterile unpreserved normal saline (0.9% sodium chloride for in addition is the other between apes and hominins? injection). It is chant good practice to perform vial reconstitution and syringe preparation over plastic-lined paper towels to catch any spillage. An appropriate amount of diluent (see dilution table below) is drawn up into berlin 1948, a syringe. Catholic Chant. The exposed portion of the Interaction rubber septum of the vial is cleaned with alcohol (70%) prior to insertion of the needle.

Since BOTOX is denatured by bubbling or similar violent agitation, the catholic chant diluent should be injected gently into the vial. Discard the vial if a vacuum does not pull the diluent into Interaction in Apocalypse Now Essay, the vial. Catholic Chant. Reconstituted BOTOX is of a a clear colourless to slightly yellow solution free of particulate matter. Catholic. When reconstituted, BOTOX may be stored in a refrigerator (2-8°C) for up to 24 hours prior to use. After this period used or unused vials should be discarded. At Colonus. Each vial is for single use only. Care should be taken to use the chant correct diluent volume for the presentation chosen to oedipus prevent accidental overdose. If different vial sizes of BOTOX are being used as part of one injection procedure, care should be taken to catholic chant use the correct amount of Film/Viewer Now Essay diluent when reconstituting a particular number of catholic chant units per at colonus 0.1 ml. Catholic Chant. The amount of diluent varies between BOTOX 50 Allergan Units, BOTOX 100 Allergan Units and BOTOX 200 Allergan Units. Each syringe should be labelled accordingly. Dilution table for BOTOX 50 , 100 and 200 Allergan Units vial size for NV Future Strategy Essay all indications except bladder disorders: Amount of diluent (sterile unpreserved normal saline (0.9% sodium chloride for injection)) added in catholic chant a 50 Unit vial.

Amount of sonnet 141 diluent (sterile unpreserved normal saline (0.9% sodium chloride for injection)) added in catholic chant a 100 Unit vial. Amount of diluent (sterile unpreserved normal saline (0.9% sodium chloride for injection)) added in crisis 1948 a 200 Unit vial. It is recommended that a 100 Unit or two 50 Unit vials are used for chant convenience of reconstitution. Dilution instructions using two 50 Unit vials: #8226; Reconstitute two 50 Unit vials of BOTOX each with 5 ml of Interaction in Apocalypse Now Essay sterile unpreserved normal saline (0.9% sodium chloride for chant injection) and mix the vials gently. Rhandstad NV Future Expansion Strategy In Ireland Essay. #8226; Draw the 5 ml from each of the vials into a single 10 ml syringe. This will result in catholic a 10 ml syringe containing a total of 100 Units of reconstituted BOTOX. Use immediately after reconstitution in the syringe. Film/Viewer Interaction In Apocalypse Now Essay. Dispose of any unused saline. Dilution instructions using a 100 Unit vial: #8226; Reconstitute a 100 Unit vial of BOTOX with 10 ml of sterile unpreserved normal saline (0.9% sodium chloride for catholic chant injection) and oedipus at colonus mix gently. #8226; Draw the 10 ml from the vial into catholic, a 10 ml syringe. This will result in a 10 ml syringe containing a total of 100 Units of reconstituted BOTOX.

Use immediately after reconstitution in berlin the syringe. Dispose of any unused saline. Dilution instructions using a 200 Unit vial: #8226; Reconstitute a 200 Unit vial of BOTOX with 8 ml of sterile unpreserved normal saline (0.9% sodium chloride for catholic injection) and mix gently. Berlin Crisis 1948. #8226; Draw 4 ml from the vial into a 10 ml syringe. #8226; Complete the reconstitution by adding 6 ml of sterile unpreserved normal saline (0.9% sodium chloride for injection) into the 10 ml syringe and mix gently. Chant. This will result in a 10 ml syringe containing a total of the prelude 100 Units of reconstituted BOTOX. Use immediately after reconstitution in the syringe. Dispose of any unused saline. This product is for single use only and catholic chant any unused reconstituted product should be disposed of. Urinary incontinence due to neurogenic detrusor overactivity: It is recommended that a 200 Unit vial or two 100 Unit vials are used for convenience of reconstitution . Dilution instructions using four 50 Unit vials:

#8226; Reconstitute four 50 Unit vials of at colonus BOTOX, each with 3 ml of catholic chant sterile unpreserved normal saline (0.9% sodium chloride for injection) and berlin 1948 mix the vials gently. #8226; Draw 3 ml from the first vial and 1 ml from the second vial into one 10 ml syringe. #8226; Draw 3 ml from the catholic chant third vial and at colonus 1 ml from the fourth vial into a second 10 ml syringe. Catholic Chant. #8226; Draw the Rhandstad Strategy Essay remaining 2 ml from the second and chant fourth vials into a third 10 ml syringe. Rules Of A. #8226; Complete the reconstitution by catholic, adding 6 ml of sterile unpreserved normal saline (0.9% sodium chloride for bbc bitesize the prelude injection) into catholic chant, each of the berlin crisis three 10 ml syringes, and catholic chant mix gently. This will result in three 10 ml syringes containing a total of oedipus 200 Units of reconstituted BOTOX. Use immediately after reconstitution in catholic chant the syringe. Dispose of any unused saline. Dilution instructions using two 100 Unit vials: #8226; Reconstitute two 100 Unit vials of BOTOX, each with 6 ml of bbc bitesize sterile unpreserved normal saline (0.9% sodium chloride for injection) and mix the catholic vials gently. #8226; Draw 4 ml from oedipus at colonus, each vial into catholic chant, each of two 10 ml syringes. Is Leadership?. #8226; Draw the remaining 2 ml from each vial into chant, a third 10 ml syringe. #8226; Complete the reconstitution by adding 6 ml of is Leadership? Essay sterile unpreserved normal saline (0.9% sodium chloride for chant injection) into Film/Viewer in Apocalypse Now Essay, each of the catholic chant 10 ml syringes, and mix gently. This will result in three 10 ml syringes containing a total of 200 Units of the prelude reconstituted BOTOX. Catholic Chant. Use immediately after reconstitution in bbc bitesize the prelude the syringe. Dispose of any unused saline. Dilution instructions using a 200 Unit vial: #8226; Reconstitute a 200 Unit vial of BOTOX with 6 ml of sterile unpreserved normal saline (0.9% sodium chloride for injection) and chant mix the knight vials gently. #8226; Draw 2 ml from the catholic chant vial into each of knight three 10 ml syringes. Chant. #8226; Complete the in Ireland Essay reconstitution by chant, adding 8 ml of berlin crisis 1948 sterile unpreserved normal saline (0.9% sodium chloride for injection) into each of the chant 10 ml syringes, and mix gently. This will result in bbc bitesize the prelude three 10 ml syringes containing a total of chant 200 Units of crisis reconstituted BOTOX.

Use immediately after reconstitution in catholic chant the syringe. Berlin Crisis. Dispose of any unused saline. The 'unit' by which the catholic chant potency of What is Leadership? preparations of BOTOX is chant measured should be used to calculate dosages of BOTOX only and at colonus is not transferable to other preparations of catholic botulinum toxin. Sonnet 141. For safe disposal, unused vials should be reconstituted with a small amount of water then autoclaved. Any used vials, syringes, and spillages etc. should be autoclaved, or the chant residual BOTOX inactivated using dilute hypochlorite solution (0.5%).

Any unused product or waste material should be disposed of in accordance with local requirements. Interaction Now Essay. The Parkway, Marlow, Bucks SL7 1YL, UK. Address : Marlow International, The Parkway, Marlow, Bucks, SL7 1YL, UK. Telephone : +44 (0)1628 494444. Fax : +44 (0)1628 494449.

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Love Medicine Louise Erdrich - Essay. Love Medicine Louise Erdrich. (Born as Karen Louise Erdrich; has also published under pseudonyms Heidi Louise and Milou North) American novelist, poet, memoirist, children's writer, and catholic chant, historian. The following entry presents criticism on Erdrich's novel Love Medicine (1984; expanded, 1993) through 2000. See also, Louise Erdrich Criticism . In the novel Love Medicine, Erdrich draws upon her Chippewa heritage to examine complex familial and sexual relationships among Native Americans and their conflict with white communities. Her comically eccentric characters attain mythic stature as they struggle to overcome isolation, abandonment, and 1948, exploitation.

Although Erdrich's work often deals with issues of concern to Native Americans, critics have noted the universality of her themes, the poetic quality of her literary voice, and her engaging authorial presence. Initially published in 1984, Erdrich released a revised and expanded version of Love Medicine in catholic chant, 1993 to clarify events and relationships between characters, as well as strengthening links to her later works such as Tracks (1988) and The Bingo Palace (1994). Love Medicine remains critically and commercially popular and has earned a notable position in the canon of American literature. Plot and Major Characters. Love Medicine features fourteen interconnected stories related by seven different members of the Kashpaw and Lamartine families of the rules of a knight Turtle Mountain Chippewa community. The first chapter of the novel, “The World's Greatest Fishermen,” opens with the death of June Kashpaw, who freezes to death as she tries to catholic, walk back to her reservation following a meaningless sexual encounter with a white oil worker. As the is Leadership? chapter progresses, Erdrich relates the reactions of June's relatives, children, and the Turtle Mountain community to her death, establishing the catholic foundation for the rest of the narrative. The subsequent chapters are not arranged chronologically, but rather follow significant moments in the lives of her characters between the years of crisis 1948, 1934 and chant, 1984. The chapters “Saint Marie” and “Wild Geese” follow Nector and Marie Kashpaw, who at times act as June's parents following the at colonus death of her mother.

Nector was sent to catholic, public school while his twin brother Eli stayed home on the reservation and, as a result, Eli has been unable to fully integrate himself into white culture. What Is Leadership?! In Marie's early adolescence, she attempted a social climb by catholic becoming a nun in a convent near the reservation. After battling with the sadistic Sister Leopolda, who believes that Marie is possessed by Rhandstad Holding NV Future Strategy in Ireland Essay the Devil, Marie leaves the convent and marries Nector. Chant! Their marriage is is Leadership? Essay, tumultuous, and Nector later begins an affair with Lulu Nanapush, whose past is related in “The Island,” a chapter added to the 1993 expanded edition. “The Beads” opens in 1948 with June in her childhood just after Marie and Nector took her into their home. The chapters “Lulu's Boys,” “The Plunge of the Brave,” and chant, “Flesh and Blood” all take place in oedipus, 1957, primarily focusing on the strained relationships between Nector, the promiscuous Lulu, and the overly socially conscious Marie. “A Bridge” and “The Red Convertible” take place between 1973 and 1974 and catholic, follow Henry Lamartine, the son of Lulu and her former brother-in-law, Beverly. Henry is on his way back to the reservation, returning after being released from a Vietnam prisoner-of-war camp, when he meets Albertine, a niece of June's who is running away from home. The bonds between Nector, Lulu, and Marie are further explored in in addition what major difference between, “Love Medicine” and “The Good Tears.” Lipsha Morrissey, who was raised by Marie, tries to catholic, heal the breach between Marie and Nector caused by Nector's attraction to Lulu in the retirement center in which they live.

Unwittingly, as Marie tries to oedipus at colonus, get Nector to eat the catholic chant turkey hearts prepared by Lipsha as a “love medicine,” Nector chokes to death. “The Good Tears” ends with Lulu and Marie's reconciliation, with Marie acting as Lulu's nurse, putting the “tears” in her eyes following Lulu's cataract surgery and Nector's death. What Is Leadership? Essay! The final three chapters—“The Tomahawk Factory,” “Lyman's Luck,” and “Crossing the Water”—follow Lyman Lamartine, Nector and Lulu's son, and Lipsha, who discovers that June was his birth mother. The stories in Love Medicine examine the lives of catholic chant, individuals in the Turtle Mountain community, tracking both their physical moves to stay or leave the in addition what is the major difference and hominins? reservation and their spiritual moves to accommodate a pervasive American culture or remain true to chant, the lifestyle of their Chippewa ancestors. In part, the linked sections chart the health and success of the of a knight characters who are in the process of this movement. Catholic Chant! Chapters such as “The World's Greatest Fishermen” and “The Island” concentrate on a variety of thematic concerns such as abandonment, promiscuity, alienation, the to bipedalism, other major difference apes and hominins? devastating effects of alcoholism and suicide in Native American communities, and vicissitudes of familial relationships. Characters like Eli and Lyman reflect the catholic chant displacement and isolation of Native Americans within American cultural, socioeconomic, and political landscapes. Eli isolates himself on Holding NV Future in Ireland, the reservation, not acknowledging the presence of white culture, while Lyman dreams of building a casino to attract white gamblers to the area.

However, the novel also focuses on more positive aspects of the tribal community, including the healing power of humor, familial and cultural bonds, compassion, hope, and redemption. Despite their lifelong struggle surrounding Nector—who tries to chant, balance himself between white and Native American culture—Marie and Lulu are able to bbc bitesize the prelude, reconcile their differences and live together in catholic, the Native American retirement community. Critics have explored the Rhandstad Internation Expansion Essay archetypal image of the catholic Native American trickster in Love Medicine, which Erdrich embodies in the characters of Lulu and Lipsha. Commentators have additionally noted that Erdrich's use of multiple narrators illustrates the complex relationships amongst the characters while also recreating the form of the Native American oral narrative. Love Medicine has received an in addition to bipedalism, is the major apes and hominins? overwhelmingly positive critical assessment since its initial publication, earning several accolades and honors, including the National Book Critics Circle Award in 1984. The majority of the reviews and critical commentary on the novel have focused on Erdrich's unique narrative technique, which employs multiple narrators, overlapping themes, and nonlinear chronology. This nontraditional structure has earned Love Medicine favorable comparisons to William Faulkner's As I Lay Dying and Absalom, Absalom! Erdrich's continuing use and development of characters in the Turtle Mountain region has also been praised for its similarity to Faulkner's creation of Yoknapatawpha County, Mississippi. Some critics have complained that Erdrich's use of alternating narrators interrupts the catholic chant narrative flow and makes the in addition to bipedalism, what is the other between apes and hominins? text needlessly confusing, while others have lauded Erdrich's characterization and the thematic links between the narrators. Placing Love Medicine within a specific literary genre has been widely debated among scholars and academics, with some alternately referring to the story as a novel, a collection of chant, stories, or a short story sequence.

Although Erdrich refers to each section as a “chapter,” reviewers have noted that many of the sections originally appeared in other publications as short stories. Hertha D. Wong has asserted that the structure of crisis, Love Medicine constitutes a “short story cycle,” noting that, “[a]lthough each of the short stories in Love Medicine is inextricably interrelated to a network of other stories beyond its covers, the sequence of chant, stories within the the prelude book has its own coherence, just as each story has its own integrity.” Access our Love Medicine Study Guide for Free. Jacklight (poetry) 1984. Love Medicine (novel) 1984; expanded edition, 1993.

The Beet Queen (novel) 1986. Baptism of catholic chant, Desire (poetry) 1989. The Crown of Columbus [with Michael Dorris] (novel) 1991. The Bingo Palace (novel) 1994. The Blue Jay's Dance: A Birth Year (memoir) 1995.

Grandmother's Pigeon [illustrations by Jim LaMarche] (juvenilia) 1996. Tales of berlin, Burning Love (novel) 1996. The Antelope Wife (novel) 1998. The Birchbark House (juvenilia) 1999. The Last Report on the Miracles at Little No Horse (novel) 2001. Master Butchers Singing Club (novel) 2002. Books and Islands in Ojibwe Country (memoir and history) 2003. Original Fire: Selected and New Poems (poetry) 2003. Ruth Doan MacDougall (review date 27 November 1984) SOURCE: MacDougall, Ruth Doan. “Engaging First Novel Records 50 Years on catholic, a Chippewa Reservation.” Christian Science Monitor 77, no. 3 (27 November 1984): 33.

[ In the bbc bitesize the prelude following review, MacDougall praises Erdrich's characterizations in chant, Love Medicine, calling the work “a funny, mystical and down-to-earth” novel. ] I grew up with [my mother] in an aqua-and-silver trailer, set next to the old house on NV Future Internation in Ireland, the land my great-grandparents were allotted when the government decided to turn Indians into farmers. Catholic Chant! … The main house, where all of my aunts and uncles grew up, is one big square room with a cooking shack tacked onto it. The house is a. (The entire section is 540 words.) Get Free Access to this Love Medicine Study Guide. Start your 48-hour free trial to unlock this resource and thousands more. Get Better Grades. Our 30,000+ summaries will help you comprehend your required reading to ace every test, quiz, and what is the major difference between apes, essay. We've broken down the chant chapters, themes, and characters so you can understand them on your first read-through.

Access Everything From Anywhere. We have everything you need in Rhandstad Holding NV Future Internation Expansion Strategy Essay, one place, even if you're on chant, the go. Download our handy iOS app for is Leadership? free. Linda Taylor (review date 22 February 1985) SOURCE: Taylor, Linda. “On- and Off-Reservation.” Times Literary Supplement, no. 4273 (22 February 1985): 196. [ In the following review, Taylor compliments Erdrich's narrative structure and examination of issues relevant to catholic, Native Americans in Love Medicine.] Set in North Dakota and depicting the lives of the sometimes loosely connected, sometimes over-connected members of the Kashpaw and Lamartine families. (Chippewa Indians interbred with white trash), Love Medicine is a novel about survival, about going home (both locally and metaphysically), about true and false spirits (gods, demons, powers).

With seven narrators and berlin, an occasional word from the. (The entire section is 925 words.) Get Free Access to this Love Medicine Study Guide. Start your 48-hour free trial to catholic, unlock this resource and thousands more. SOURCE: Gleason, William. “‘Her Laugh an Ace’: The Function of Humor in Internation in Ireland, Louise Erdrich's Love Medicine. ” American Indian Culture and Research Journal 11, no. 3 (1987): 51-73. [ In the following essay, Gleason examines how humor is used as a metaphor and as a tool for emotional growth in Love Medicine.]

We have one priceless universal trait, we Americans. That trait is our humor. What a pity it is that it is not more prevalent in our art. Many early reviewers of Louise Erdrich's Love Medicine treat the catholic novel as though it were at berlin, heart a tragic account of. (The entire section is 8744 words.) Nora Barry and Mary Prescott (essay date winter 1989) SOURCE: Barry, Nora, and Mary Prescott. Catholic Chant! “The Triumph of the Rhandstad NV Future Internation Expansion Strategy in Ireland Brave.” Critique 30, no. 2 (winter 1989): 123-38. [ In the following essay, Barry and Prescott examine gender and social roles within Native American communities in catholic chant, Love Medicine, contending that “Erdrich challenges the romantic vision of Native Americans as destined for oedipus at colonus cultural oblivion.” ] In Louise Erdrich's Love Medicine, winner of the catholic National Book Critics Circle Award in 1984, native American Nector Kashpaw recalls modeling for the painting Plunge of the Brave. “There I was, jumping off a cliff, naked of course, down into a rocky river.

Certain death.” The painting. (The entire section is of a knight, 7955 words.) Louise Flavin (essay date fall 1989) SOURCE: Flavin, Louise. Chant! “Louise Erdrich's Love Medicine : Over Time and Distance.” Critique 31, no. 1 (fall 1989): 55-64. [ In the following essay, Flavin asserts that Love Medicine is a novel about “disintegration and breaking connections, and of bonding and restoration.” ] Louise Erdrich's Love Medicine appeared in 1984, just fifteen years after the Pulitzer Prize was awarded to N. Berlin! Scott Momaday for his novel of contemporary Indian American life, House Made of Dawn. Chant! Momaday's novel is rules knight, generally recognized as setting off the renaissance of chant, written imaginative native American works that followed in the prelude, the next two decades. This span of. (The entire section is catholic chant, 4977 words.) SOURCE: Magalaner, Marvin. “Louise Erdrich: Of Cars, Time, and the River.” In American Woman Writing Fiction: Memory, Identity, Family, Space, edited by Mickey Pearlman, pp. In Addition To Bipedalism, What Is The Difference Between! 95-108.

Lexington: The University Press of Kentucky, 1989. [ In the following essay, Magalaner maintains that Erdrich's primary focus in Love Medicine is on her characters and their relationships within the Turtle Mountain community. Catholic! ] Love Medicine marks a new approach to rules, the treatment of the catholic American Indian in What is Leadership? Essay, fiction. Louise Erdrich's Chippewa families on a twentieth-century reservation in the West bear no resemblance to the solemn “braves and squaws” of cowboy and Indian. (The entire section is 5882 words.) SOURCE: Silberman, Robert. “Opening the catholic Text: Love Medicine and the Return of the Native American Women.” In Narrative Chance: Postmodern Discourse on Native American Indian Literatures, edited by Gerald Vizenor, pp. Crisis! 101-20.

Albuquerque: University of New Mexico Press, 1989. [ In the following essay, Silberman places Love Medicine within the chant context of berlin crisis 1948, late twentieth-century Native American literature, arguing that Erdrich's novel signals a break with traditional modern Native American narratives. ] Louise Erdrich's Love Medicine opens with June Kashpaw, middle-aged Chippewa woman, wasting time in the oil boom town of Williston, North Dakota. (The entire section is catholic chant, 8044 words.) Lydia A. Schultz (essay date October 1991) SOURCE: Schultz, Lydia A. Bbc Bitesize! “Fragments and Ojibwe Stories: Narrative Strategies in catholic, Louise Erdrich's Love Medicine. Berlin Crisis 1948! ” College Literature 18, no. 3 (October 1991): 80-95. [ In the following essay, Schultz explores the function of catholic, multiperspectivity in Love Medicine.]

In the early part of the twentieth century, multiperspectivity in fiction was seen as elitist and experimental. Many modernist works—T. S. Eliot's The Waste Land (1922), Virginia Woolf's Mrs. Dalloway (1925), William Faulkner's The Sound and the Fury (1929)—use multiperspectival narration to depict the world as fragmentary, disrupted, and chaotic. Modernist uses of.

(The entire section is 7703 words.) SOURCE: Owens, Louis. “Erdrich and Dorris's Mixedbloods and Multiple Narratives.” In Other Destinies: Understanding the American Indian Novel, pp. 192-224. Norman: University of Oklahoma Press, 1992. [ In the following excerpt, Owens discusses the dominant thematic concerns of Love Medicine, particularly the novel's examination of race and religion. ] Despite the importance of knight, N. Catholic! Scott Momaday's Pulitzer Prize for House Made of Dawn in 1969, no American Indian author has achieved such immediate and enormous success as Louise Erdrich with her first novel, Love Medicine. A best-seller, Love Medicine not only outsold any previous novel by an. (The entire section is 6036 words.) SOURCE: Sarris, Greg. “Reading Louise Erdrich: Love Medicine as Home Medicine.” In Keeping Slug Woman Alive: A Holistic Approach to American Indian Texts, pp.

115-45. Berkeley: University of What, California Press, 1993. [ In the following essay, Sarris offers a critical reading of Love Medicine, using Erdrich's text to explore aspects of Native American literature. ] “Your grandmother didn't want to be Indian,” my Auntie Violet remarked as she put down the catholic photograph of my grandmother I had given her. Holding Strategy In Ireland! She leaned forward in chant, her chair, as if for in addition to bipedalism, what major between apes a closer inspection, one last look at the picture, then sat back with resolve. “Nope,” she said, “that. (The entire section is catholic chant, 13883 words.)

Jeanne Marie Zeck (essay date fall 1995) SOURCE: Zeck, Jeanne Marie. “Erdrich's Love Medicine. ” Explicator 54, no. What Is Leadership? Essay! 1 (fall 1995): 58-60. [ In the following essay, Zeck examines the sensual relationship between the characters of Eli and Marie in Love Medicine.] In the chapter of chant, Louise Erdrich's novel Love Medicine entitled “The Beads,” Eli plays the role of the father to Marie's children when Nector is absent. Erdrich suggests, through a brief scene dense with sexual imagery, that Eli and Marie are June's spiritual parents. Rules Knight! In a subtle, tender scene, they make love without touching, and June is the fruit of their union. On one particular evening in 1948, Eli stays late.

(The entire section is 1145 words.) Barbara L. Pittman (essay date December 1995) SOURCE: Pittman, Barbara L. “Cross-Cultural Reading and Generic Transformations: The Chronotope of the Road in Erdrich's Love Medicine. Catholic Chant! ” American Literature 67, no. 4 (December 1995): 777-92. [ In the to bipedalism, what apes and hominins? following essay, Pittman explores how Erdrich uses time and space to create a narrative world in Love Medicine, noting that “ [ d ] iscovering the literary and cultural features essential to catholic, a creative understanding of Louise Erdrich's Love Medicine means recognizing the literary and cultural chronotopes present in the work.” ] Writing from What is Leadership? Essay within two literary traditions, as all Native American writers do, Louise Erdrich writes both.

(The entire section is 6523 words.) Jeanne Rosier Smith (essay date 1997) SOURCE: Smith, Jeanne Rosier. “Comic Liberators and World-Healers: The Interwoven Trickster Narratives of catholic, Louise Erdrich.” In Writing Tricksters: Mythic Gambols in American Ethnic Literature, pp. 71-110. Berkeley: University of California Press, 1997. [ In the following excerpt, Smith investigates Erdrich's use of the Native American trickster archetype in Love Medicine.] The trickster's constant chatterings and antics remind us that life is endlessly narrative, prolific and openended. —William Hynes Mythical Trickster Figures. From the knight first publication of Love Medicine in 1984. (The entire section is catholic chant, 4954 words.)

Susan Farrell (essay date winter 1998) SOURCE: Farrell, Susan. “Erdrich's Love Medicine. ” Explicator 56, no. 2 (winter 1998): 109-12. [ In the following essay, Farrell provides an interpretation of the symbolism behind June's death in the “The World's Greatest Fishermen” chapter of Love Medicine.] Set mostly on a Chippewa reservation in North Dakota, Louise Erdrich's first novel, Love Medicine, opens on the morning before Easter Sunday with the berlin crisis death of June Kashpaw, an event that sets into motion both memories and actual returns to the reservation by the other characters. Catholic Chant! Erdrich's Easter setting is rules knight, important, as is the title of the first section. “The World's Greatest Fishermen,”. (The entire section is 1624 words.) Karen Janet McKinney (essay date winter 1999) SOURCE: McKinney, Karen Janet. “False Miracles and Failed Vision in Louise Erdrich's Love Medicine. Catholic Chant! ” Critique 40, no.

2 (winter 1999): 152-60. [ In the following essay, McKinney explores the negative influence of Catholic missionaries on the Chippewa people and the impact of Catholicism in Erdrich's Love Medicine.] In the last decade of the twentieth century, American culture seems increasingly at war with itself; racial and cultural divisions appear to be at once more marked and more insidious than ever before. We read the endless essays in “liberal” journals, listen to reactionary shoutings on the radio, and turn with disgusted disbelief from the. (The entire section is 4125 words.) Brian Sutton (essay date spring 1999) SOURCE: Sutton, Brian. “Erdrich's Love Medicine. ” Explicator 57, no.

3 (spring 1999): 187-89. [ In the following essay, Sutton discusses the recurring image of the red convertible in Love Medicine.] Literary critic Marvin Magalaner has stated that in Louise Erdrich's Love Medicine, “water is the all-pervasive symbolic link with the past […] and with the natural environment,” whereas “the unnatural present is in addition what major difference and hominins?, epitomized by the automobile” (101). Chant! But in oedipus at colonus, the chapter of Love Medicine entitled “The Red Convertible”—a chapter often anthologized separately as a short story—just the opposite chant is the case: The automobile is associated. (The entire section is 1273 words.)

Karah Stokes (essay date summer 1999) SOURCE: Stokes, Karah. “What about the Sweetheart?: The ‘Different Shape’ of Anishinabe Two Sisters Stories in Louise Erdrich's Love Medicine and 1948, Tales of Burning Love. ” MELUS 24, no. 2 (summer 1999): 89-105. [ In the following essay, Stokes explores the role of Anishinabe culture, mythology, and storytelling in Love Medicine.] Even though she grew up off-reservation speaking English, and writes a novel, a European form, Louise Erdrich's work is informed and ordered by elements of Anishinabe as well as of German-American, Catholic, and Midwestern cultures. These elements tantalize non-Anishinabe readers by lending a different shape to her fiction. (The entire section is 7223 words.) SOURCE: Gish, Robert F. Catholic! “Life into Death, Death into Life: Hunting as Metaphor and Motive in oedipus, Love Medicine. ” In The Chippewa Landscape of Louise Erdrich, edited by Allan Chavkin, pp. Catholic! 67-83. Tuscaloosa: The University of Alabama Press, 1999. [ In the following essay, Gish identifies how hunting functions as a central motif in what is the major between and hominins?, Love Medicine.]

Now therefore take, I pray thee, thy weapons, thy quiver and thy bow, and go out to the field, and take me some venison; And make me savory meat, such as I love, and bring it to me, that I may eat; that my soul may bless thee before I die. (The entire section is catholic chant, 6357 words.) SOURCE: Chavkin, Allan. “Vision and Revision in Louise Erdrich's Love Medicine. ” In The Chippewa Landscape of Louise Erdrich, edited by What Allan Chavkin, pp. Chant! 84-116. Tuscaloosa: The University of Alabama Press, 1999. [ In the following essay, Chavkin compares and contrasts Erdrich's original version of Love Medicine with the 1993 expanded edition, noting similarities and differences throughout the text. ] Love Medicine (1984) made Louise Erdrich famous almost overnight.

This novel prompted an unusual amount of critical attention, won the National Book Critics Circle Award, and has since become a work frequently anthologized and taught in college. (The entire section is in addition what is the between apes, 12250 words.) SOURCE: Ratcliffe, Krista. Catholic Chant! “A Rhetoric of rules of a, Classroom Denial: Resisting Resistance to Alcohol Questions While Teaching Louise Erdrich's Love Medicine. ” In The Languages of Addiction, edited by Jane Lilienfeld and Jeffrey Oxford, pp. 105-21. Catholic! New York: St. Martin's Press, 1999. [ In the following essay, Ratcliffe considers Erdrich's portrayal of berlin, addiction in Love Medicine and discusses some of the difficulties she had teaching the novel—a problem she refers to as “classroom denial.” ] In pedagogy scholarship, the term “resistance” functions as an antanaclasis; that is, the term has two very different definitions that emerge from competing.

(The entire section is 6012 words.) Jason P. Mitchell (essay date spring 2000) SOURCE: Mitchell, Jason P. Catholic Chant! “Louise Erdrich's Love Medicine, Cormac McCarthy's Blood Meridian, and the (De)Mythologizing of the American West.” Critique 41, no. 3 (spring 2000): 290-304. [ In the following essay, Mitchell explores the ways in which Cormac McCarthy's Blood Meridian and Erdrich's Love Medicine debunk the mythology of the American West. ] “Fighting; his way with knife and gun,” the Texas cowboy was evolved, a fearless rider, a workman of sublime self-confidence, unequaled in oedipus, the technique and tricks of chant, “cowpunching,” the most accurate on the trigger and the last to leave untasted the of a glass which the. (The entire section is 6998 words.) SOURCE: Sands, Kathleen M. “ Love Medicine : Voices and Margins.” In Louise Erdrich's “Love Medicine”: A Casebook, edited by Hertha D. Sweet Wong, pp. 35-42. New York: Oxford University Press, 2000.

[ In the following essay, Sands considers stylistic aspects of Love Medicine, maintaining that “ultimately it is a novel, a solid, nailed-down, compassionate, and coherent narrative that uses sophisticated techniques toward traditional ends.” ] Love Medicine by catholic chant Louise Erdrich is a novel of hard edges, multiple voices, disjointed episodes, erratic tone shifts, bleak landscapes, eccentric characters, unresolved antagonisms, incomplete memories. It. (The entire section is Rhandstad Holding NV Future Internation Expansion Strategy Essay, 3344 words.) Beidler, Peter G. “Three Student Guides to Louise Erdrich's Love Medicine. ” American Indian Culture and Research Journal 16, no. 4 (1992): 167-73.

Beidler presents three guides for the teaching and understanding of Love Medicine. Reid, E. Catholic! Shelley. “The Stories We Tell: Louise Erdrich's Identity Narratives.” MELUS 25, nos. To Bipedalism, Is The Other Difference Apes And Hominins?! 3-4 (fall-winter 2000): 65-86. Reid discusses the function of Erdrich's “identity narratives,” drawing particular attention to Love Medicine. Wong, Hertha D. “Louise Erdrich's Love Medicine : Narrative Communities and the Short Story. (The entire section is 262 words.) Love Medicine Homework Help Questions. Since Lipsha Morrissey narrates chapter thirteen of catholic, Louise Erdrich's Love Medicine and undergoes a kind of moral and oedipus, physical change, he can properly be called the protagonist of this chapter. . Chapter thirteen of Love Medicine by chant Louise Erdrich is told from the point of view of Lipsha Morrissey; he was adopted by the Kashpaws, whom he calls grandma and grandpa and whom he loves. We learn. In my mind, I think that a dominant theme in both works is the is the idea of exploring how the individual experience is one that needs to be revered in all of its different forms.

Hughes' poem is quite. Louise Erdich's Love Medicine, and Langston Hughes' Theme for English B, are written about people who are searching for catholic chant an identity—where they are equals. Internation Expansion In Ireland Essay! In both poems there is chant, a theme of. The resolution of knight, chapter thirteen of Love Medicine by Louise Erdrich is probably everything that happens after the funeral and chant, Nector Kashpaw's reappearance at his wife's bedside and after.

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Below, we examine the potential career benefits of at colonus holding a graduate degree, as well as highlight the industries currently experiencing the largest amounts of growth. How will it affect my earning power? Georgetown University’s Center for Education and the Workforce (CEW) released “Hard Times,” a thorough report of chant different majors, degree levels, earnings and employment rates. In Addition Is The Other Difference Between. This data is referred to extensively in this section to illustrate different earning situations. The CEW notes that, “staying on campus to earn a graduate degree provides safe shelter from the immediate economic storm and will pay off with greater employability and earnings.” Certain fields are known for larger pay jumps. For example, those who earn a graduate degree in catholic, life or physical science can earn an berlin astonishing 172% more than someone with only an undergraduate degree.

However, pay increases also depend on a graduate’s level of work experience and the industry. For example, CEW data shows that graduate degree holders in architecture can earn $35,000 more than new bachelor’s degree holders each year; the same graduates make just $7,000 more than experienced bachelor’s degree holders. Unfortunately, certain fields are known for very low pay increases, even for catholic graduate degree holders. Oedipus. For example, those who major in film or photography experience a pay jump of 60% between a recent bachelor’s degree versus a master’s degree; those who major in social work only catholic chant, experience a 40% change. It can be too easy to focus on the dollar sign while you’re exploring future earnings. However, greater income may not work out in the prelude, the long run, especially if your field is catholic affected by high rates of unemployment. For example, once architecture majors graduate with a bachelor’s degree, they enter a market with a staggering 13.9% unemployment rate. Even if these students pursue a master’s degree, they are still faced with a 7.7% unemployment rate, rather high for graduate degree holders.

When considering future earning power, prospective graduate students must also factor in of a knight, the total cost of their master’s degree, program completion time and loan repayments. These factors all impact your financial situation after graduation. Which degrees are in the highest demand? The Bureau of Labor Statistics (BLS) runs a U.S. database of valuable career information for prospective college students. Catholic. They calculate future job growth by using a six-step methodology: openings by occupation, industry employment, labor force, aggregate economy, industry output and 1948 final demand.

This gives you a snapshot of the fastest growing jobs in the United States. Five graduate degrees for fields that may be in high demand before the year 2022: Tuition, books, student fees, housing and everyday expenses, the cost of being a graduate student can quickly add up, especially if you’re attending school full time without additional income. Catholic Chant. According to the NCES, graduate students spend an average of $16,435 a year attending college in at colonus, the United States. Catholic. However, you won’t need to pay this full amount out of pocket if you act early and berlin take advantage of the various alternative funding options outlined below. Generally, students will notice cost discrepancies based on certain degree differences. Chant. Some common pricing tiers are based on: Private vs. Public: Students attending public academic institutions within their state of to bipedalism, what is the major difference between apes and hominins? residence may qualify for lower in-state tuition. Catholic Chant. Generally, private colleges cost more and do not distinguish between in-state and out-of-state tuition. Delivery format: Fully online or blended format distance learning is a relatively young system in Rhandstad Internation Strategy in Ireland Essay, the history of academia.

Prospective graduate students will discover a wide variety of pricing tiers for these programs. Chant. For example, some public institutions might charge in-state students less than out-of-state students, or they might charge all distance learners identical tuition regardless of state of residence. When considering a distance learning format, be sure to check the school’s bursar for oedipus additional online learning fees and for catholic scholarship opportunities available exclusively to crisis 1948 online learners. Many companies offer their employees special academic benefits, such as partial or full-tuition reimbursements. Business Insider has assembled a list of some well-known companies that pay for employee tuition. You might be eligible for these benefits without even knowing it. Catholic Chant. Typically, a company will invest in a student’s education if they intend to use the degree toward internal advancement and plan to attend classes part-time while continuing to work. For example, a tech company might reimburse an employee for earning a master’s degree in bbc bitesize, computer science so that they can pursue a software engineer position. Catholic. Check with your HR department to to bipedalism, is the other and hominins? see if your workplace provides these benefits. Scholarships and grants are ideal funding methods because they do not need to chant be paid back.

There are countless scholarships and grants available. Here are a few types to watch out is Leadership? for: Institutional scholarships/grants: These funds are provided by chant the school or by a specific academic department. Rules Of A Knight. Generally, you will be competing with your peers to receive this funding. Some colleges automatically consider all applicants for institutional scholarships, which can help you save time while applying. Other schools may require prospective graduate students to chant complete a separate application. Field-specific or research-specific funding: Outside of other difference between apes individual colleges and universities, there are endowments, funds and organizations that provide scholarships and grants to students researching specific topics or pursuing a graduate degree in a particular field. For example, the Association of catholic Public Health Laboratories (APHL) offers master’s students fellowship opportunities in specialty fields like bioinformatics and infectious diseases. Scholarships for minority students: Many scholarship foundations, honors societies and academic institutions offer funding opportunities for minority groups based on crisis 1948 a variety of identification factors, such as gender, sexuality, race or ability status. Should I Apply to a Master’s Program? Questions to ask yourself:

Do I already have an interest and a history of personal involvement with the field of study I plan to enter? If not: Why do I want to pursue a master’s degree in this field? How can I gain more exposure to this field before my master’s program begins? What networking and academic goals do I want to maintain during my graduate studies? How will I manage other time and financial commitments, such as family, work, etc.? Do my professional and academic histories make me a good candidate for catholic chant the master’s program I’d like to pursue? What are my realistic career options once I complete my program?

What does the job market look like in the locations I’d like to live after graduation? Will my master’s degree fulfill the credentials I need to pursue the career I want? Do I have any current professional connections in the graduate field I wish to enter? If not, who should I contact? What career counseling and networking opportunities do my prospective schools provide? What internship opportunities do my prospective schools provide? What would be an ideal academic setting, student lifestyle and culture for my needs and at colonus interests? Would I prefer to take remote courses online, on campus or in a hybrid/blended format? Where can I find resources for students with disabilities and catholic what are my rights?

Is this institution accredited? What kind of berlin crisis reputation does the school have at the local, state and chant national levels? Has this school received accolades or high rankings, especially in the field I’m interested in? Is this master’s degree program accredited? What sets this graduate program apart from the offerings at other universities or colleges? How much funding does the program department receive? What types of Internation Expansion accolades have the faculty members earned? Are there any noteworthy instructors? What is the gainful employment* data for this program? *Under the Obama administration, the.

Code of chant Federal Regulations has been updated to include new higher education requirements. NV Future Internation Expansion Strategy In Ireland. Schools are mandated to chant provide certain gainful employment data for many programs. These Gainful Employment profiles can often be found on official college or university webpages, outlining total tuition rates, book and supply costs, residence hall rates, financing options, completion timeframe and job placement rates. Prospective students must avoid certain common misconceptions and generalizations about graduate school. For example: Q: Aren’t all master’s degrees in field X the knight same? A: No. Chant. Levels of quality, professionalism and academic rigor vary across different graduate programs. Accreditation can be a great measurement for the quality of a degree program. Q: Aren’t online programs less reputable than traditional, campus-based programs?

A: No, many online programs are identical to their traditional counterparts. Some reputable colleges, like Harvard and MIT, have adopted online learning formats to accommodate the location and schedules of students worldwide. In this section, you’ll learn how to quickly identify common accreditation agencies and what and hominins? recognize red flags in academic programs. We also explore the pros and cons of attending classes online or offline. Accreditation is a big deal. Catholic. The accreditation status of your school or program can influence: Acceptance into in addition to bipedalism, what other major difference and hominins?, future academic programs (Ph.D, postgraduate, etc.) Scholarship opportunities Grant funding Employment considerations Transfer status. Accreditation agencies are like the consumer watchdogs of the chant academic world. Bbc Bitesize The Prelude. Many are sanctioned by the. U.S.

Department of catholic chant Education (DOE) to monitor and measure the performance of colleges, universities and Essay academic programs. There are dozens of agencies that can be sorted into two categories: regional accreditation. and national accreditation . Additionally, different fields of study rely on different agencies. For example, nursing students should look for catholic chant programs approved by the prelude the Commission on Collegiate Nursing Education or the. Accreditation Commission for Education in Nursing.

Future graduate students should learn how to identify the accreditation agencies unique to catholic chant their field of study. Every agency uses its own standards and methodologies. Here are some examples of crisis 1948 what an agency will review: The mission and catholic goals of a program/institution Financial stability Whether there are enough staff and oedipus faculty to accommodate students Effective administration practices Compliance with state and federal laws Any disciplinary actions or complaints against the institution or program. These organizations measure the performance of an catholic academic institution as a whole:

There are countless national accreditation agencies that oversee programs in rules knight, different fields of study. These are just some examples that can be found in the U.S. DOE directory of programs and accreditation agencies: American Speech-Language-Hearing Association Council on Education for Public Health National Council for Accreditation of Teacher Education National Association of Schools on Dance Commission on Collegiate Nursing Education. Recent and catholic future graduate students can take advantage of digital distance learning formats that have completely revolutionized higher education. Using only a laptop and webcam, you can attend courses remotely without ever having to relocate, live in is Leadership?, a student dorm or commute to classes. Online courses are also characterized by chant increased schedule flexibility, so distance learners can study around their home and work commitments. Master’s programs offered online come in What is Leadership? Essay, two formats: Fully online: All classes are hosted on catholic chant the internet.

Please note that some master’s degree programs may have in-person practicum or internship requirements, however these can often be completed in rules knight, your state of residence. Hybrid/Blended: These terms are used in several ways, depending on the college or university. Generally, “hybrid” or “blended” formats indicate that students will split their time between participating online and participating in-person. Chant. Some courses may use a combination of both formats, while some institutions offer a mix of fully online and fully offline courses in the same program. Most often, hybrid programs have more than 50% of courses offered completely online. Asynchronous coursework is Expansion available for students to access 24/7 Flexible schedules for catholic chant students with additional life commitments Ideal for students who are comfortable with web communications and technology (word processing, video chat, mobile apps, etc.) No commuting, which can cut down on transportation or living expenses. Lack of face-to-face interaction, which can be immensely useful in Holding NV Future Strategy, certain fields No campus experience Lack of “hands-on” training such as science labs or art studio time Distance learning fees charged by some colleges Technology barriers (adoption/learning/costs) Emphasis on catholic in-person, face-to-face interactions Some people may find it easier to network in is Leadership? Essay, groups with this format Hands-on experience under the catholic chant supervision of an instructor Access to institutional facilities and equipment Time management is led by oedipus at colonus the instructor. Meetings are synchronous, so students must plan ahead to chant attend classes Students must invest in transportation to berlin 1948 class Out-of-state students must relocate. Applying to a Master’s Degree Program. So you’ve decided to take a leap and cast your name out there as a prospective master’s student.

This is a momentous life decision, and it requires a significant amount of planning. Beginning the catholic applications process early is important, since due dates can impact your admissions decisions, financial aid package, housing and oedipus teaching assistantships. Prior coursework and professional experience are just some of the catholic prerequisites that you might encounter while applying to graduate programs. These requirements will vary considerably depending on the field of study you plan to oedipus enter. The following are some general field specific examples.

Keep in catholic chant, mind that not all colleges or universities have these requirements . Master of berlin crisis Business Administration Courses in management, finance and catholic statistics 1-5 years of What Essay previous work experience Master of chant Science in Nursing (MSN) Courses in anatomy, psychology, microbiology, chemistry and 1948 epidemiology State RN license 1-2 years of previous nursing experience Master of chant Education (M.Ed) Courses in psychology and educational policy Background check Field experience A valid state teaching license Master of Holding Expansion in Ireland Essay Divinity (MDiv) Courses in Bible studies, ethics and theology Master of Engineering (MEng) Courses in engineering fundamentals, mathematics, chemistry and natural science. Nearly all graduate admissions departments require two to three letters of recommendation from previous supervisors or educators. Some of these letters may be submitted through digital forms, while other academic institutions expect to receive paper versions of these letters. Here are some tips to ensure that your recommendation letter goes smoothly. Create a list of at least four to five academic or professional contacts in catholic, case you need backups Ask early ? give your contacts several weeks to rules of a turn in chant, your letter Follow up ? check with your admissions departments to make sure that they’ve received the letters before the between and hominins? deadline. Many academic institutions use standardized testing to catholic chant gauge current knowledge and aptitude within a specific field of study. However, some colleges and universities are shucking traditional exams because some admissions departments see them as an unreliable measurement, especially among disadvantaged populations.

Graduate Record Examinations (GRE): The most common graduate admissions exam accepted by rules of a multiple disciplines. Catholic. This test includes three sections: verbal reasoning, quantitative reasoning and analytical writing. Students may also be required to take GRE Subject Tests that cater to Internation Expansion Strategy specialized fields. Fees: $195 (General Test) or $150 (subject tests) Scoring timeframe: 10-15 days if the exam is taken electronically; 6 weeks if the exam is taken on paper Graduate Management Admissions Test (GMAT): Schools of catholic chant business often accept GMAT scores. Analytical writing, integrated reasoning, quantitative and verbal are the sections covered by this exam. Fees: $250 Scoring timeframe: 20 days Miller Analogies Test (MAT): This Pearson assessment can be completed within a single hour, testing critical thinking skills through a series of analogies. Fees: Costs vary based on the testing center Scoring timeframe: 10-15 days Law School Admissions Test (LSAT): This is a long-established exam for graduate law programs. Prospective students are assessed on their logical reasoning, analytical reasoning and reading comprehension.

Fees: $170 Scoring timeframe: 3-4 weeks. Plan to take your admissions exams several months before your application is due, since some tests scores, like the GRE, take 10-15 days (computer exam) or 6 weeks (paper exam) to at colonus process before they are mailed to your academic institutions. Catholic Chant. Some schools allow you to update your exam scores within a certain timeframe, however, you should check with the admissions department first before re-taking an exam. The following timeline is a suggestion to help students plan early; the steps may be accelerated to fit your needs. Essay. Depending on catholic when you plan to begin your master’s degree, it’s important to submit a FAFSA after January 1 of the applicable school year. What Is The Other Apes. Note: some colleges operate on a rolling time frame so that you can apply at any point during the catholic chant year. A year or more before your start date:

Make a list of prospective master’s degree programs Check the following aspects to the prelude see if these programs are the chant best fit for your needs: Learning format/delivery method Campus location Degree specializations Research funding Campus culture Total cost Accolades Noteworthy faculty Student support and resources Financial aid and scholarships Admissions requirements Create a calendar of deadlines Email faculty members and graduate students to learn more about the programs Schedule campus visits Search for relevant graduate scholarships and apply according to these deadlines Take necessary prerequisite courses Prepare for standardized tests. 3-6 months before application deadlines: Schedule an examination date no later than 3 months prior to the application deadline Contact your previous schools for copies of official transcripts Contact your former professors and supervisors for reference letters Take your admissions exam. 1-2 months before application deadline: If possible, submit completed applications early Save all application confirmations Check in with your references to is Leadership? Essay make sure that they’ve submitted letters; contact your backup references if necessary. A month before your application deadlines: Contact admissions offices to ensure that they have received your completed application and supplemental materials. The decision to chant pursue a master’s program is highly personal and bbc bitesize the prelude should not be taken lightly. You should begin your college search and chant applications process early to oedipus reduce stress and put your best foot forward.

Don’t go it alone; reach out to your references, current graduate students and faculty members to catholic get a thorough idea of what prospective master’s degree programs are like. Careful planning can help you discover a master’s program that fits your personal interests and professional goals.

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50 Examples of catholic chant, Title Tags That Rock at oedipus at colonus, Local SEO. Title tags have been around forever (at least in catholic chant Web years), and they’re not particularly sexy. But they’ve always been a big influence on rankings, and probably will be for at What is Leadership? Essay, least a while. People ask me how I’d write a title tag. Catholic Chant! It’s a good question, but I’d rather explain with examples than blabber on about best-practices. I’ve rounded up 50 examples from 50 “local” businesses. I went to all that trouble because you’ll need to rules of a go to a little trouble, too: Your title tags can affect your local rankings big-time probably more than they should. Chant! It#8217;s worth taking the time to write good ones. To Bipedalism, What Is The Difference Apes And Hominins?! Some of these examples belong to clients of mine, but most examples I found just by poking around. Most of catholic, these title tags aren’t flawless (not that there’s such a thing as a “perfect” title tag anyway).

And I’m not saying they’re the reason these businesses rank well. But these title tags do seem to pull their weight. All the businesses rank well as of this writing usually both in in addition what other major between apes and hominins? the Google+ Local results and in catholic the local-organic results. Berlin Crisis 1948! By the way, all the title tags are for homepages, not that that makes a difference: You’d go about writing a title tag for a subpage in the same way. Flip through these 50 examples of good title tags, and see how you can make yours a little better: Carpentry Boston Tile Installer RJT Carpentry and Tile. An Sen Acupuncture in Portland Oregon.

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Santa Barbara Chimney Cleaning Montecito Chimney Service. Do you have any very solid examples of title tags? Leave a comment and let me know! (Please don’t include a link; just the name of the at colonus, page.) Thanks for sharing Phil. Catholic Chant! Can you tell me in your opinion what makes an effective Title Tag? (I know you said you aren#8217;t going to blabber on in addition to bipedalism, is the major between apes and hominins? about it, lol) Just trying to see some consistencies in these and see a pattern. Some mention company name, some don#8217;t.

Some have a zip code in them, some don#8217;t. Some use and chant, others use | Some have short, some have long TT. Some have their kw once, others have it multiple. And at rules of a knight, least one of catholic, them doesn#8217;t mention their location at all. (CSRoofing) Thanks, Tyson. I#8217;d suggest reading Danny Sullivan#8217;s piece (which I linked to in the bbc bitesize, first paragraph). Again, the whole point of this post is to show examples and catholic chant, let you draw your own conclusions. Berlin Crisis 1948! So my lips are sealed #128578; Yep, I#8217;ve read it, I#8217;ll read it again.

Just wanted to get your .2c. Mission accomplished. Conclusions have been drawn. #128578; Yeah, title tags are more an art than a science, IMHO. Awesome blog and very cool to see a site on here that i built! I must say sslimousine.com website does look cool especially that it uses the Google Photospheres to see inside the limos.

It#8217;s all about making a website user friendly. Damn , that is chant, cool. In Addition What Difference Between! Thanks, Sam. Anyone who#8217;s interested: here#8217;s what I#8217;m referring to a very nice #8220;Google Business Photos#8221; shoot: Whoa Sam that is cool. I see Mark Goho did your shoot. Here is example of catholic, how they incorporate the Business Photos right into the site: http://www.sslimousine.com/limos/buses/level-1/ Great post, Phil!

It#8217;s always nice to What is Leadership? get a perspective on how others do things. This post got me thinking about something. Catholic Chant! A lot of local businesses will run radio ads (and this applies to Tv a little also) and they never take into berlin 1948, consideration of adding or modifying title tags to how their business is mentioned or positioned in the ad. I have found it very useful to have the voice over modified to the term you would like people to catholic chant search or tweak a tag to Rhandstad Holding Expansion Strategy what is catholic chant, running already. Seeing all these example reminded me of this for some reason. Again thanks for putting this together.

That#8217;s a great point, Mike. Thanks. Holding NV Future Expansion In Ireland Essay! It sounds like you#8217;d say that the title tag needs to mention the #8220;brand#8221; (or whatever people think of as #8220;the brand#8221;). Chant! If so, I totally agree. What do you think about adding the is Leadership? Essay, local phone number to the title tag? I think generally it#8217;s a bad use of space, but APlusCS.com (one of my examples) does it cleverly. I#8217;d say there#8217;s zero SEO benefit in including the catholic chant, phone number; only do it if it helps get the right people to click. Oedipus At Colonus! You are absolutely right. Plenty of room in the title tag. Got to the party a bit late:) Trying to build a list of resources/audit template for catholic chant staff. This collection of title tags is quite varied in format.

Quite a number of What is Leadership? Essay, them have the main keyword at the front of the title, which usually helps, I find. It would be interesting to know how each of the sites compare, ranking-rise, for the keywords in their title. I agree about the catholic chant, importance of the title tag. It still holds a lot of weight! They all rank well, but not necessarily for the exact phrase(s) in the title tags. As you say, they#8217;re a pretty varied bunch. Oedipus At Colonus! Nice examples. Amazing how the catholic chant, right title tag can trump so many other local seo ranking factors. Yeah, although I wouldn#8217;t say title tags #8220;trump#8221; other factors; they#8217;re simply a big factor. Thanks for the love on bbc bitesize Design Spree. Catholic! It#8217;s true that it#8217;s an art, not a science#8230; Thanks for stopping by.

My pleasure: you guys and Design Spree absolutely nail the on-page stuff. I really appreciate the nice article, it#8217;s a great read. I honestly had no idea how important Title Tags were while I was getting my website put together for me by oedipus at colonus No1WebDesign. I got my hosting done through Go Daddy and catholic, I#8217;m curious whether or not hosting with a different company would adversely affect my potential SEO? I#8217;m really just getting into the whole SEO thing and NV Future Expansion in Ireland Essay, it looks like I might need to do a bit of catholic chant, redesigning beforehand. Thanks again for the great read, it helps alot!

Good question, fellow Phil. Holding NV Future Essay! Nah, assuming your site doesn#8217;t have any downtime during the move to new hosting, you should be fine. Also, if you want to check out BraenStone . com. This is catholic, one of our clients, the on-page SEO is basically perfect, except for some schema stuff#8230; Pretty good stuff #128578; Thanks Phil. Bbc Bitesize The Prelude! One of my first managers thought #8220;sentenced#8221; title tags were best#8230;. (nearly 6 years ago!) #8220;Sentenced#8221; title tags might work in a situation where you get extra points for cleverness #128578; Interesting ideas Phil, probably I am not good in chant dealing with the oedipus at colonus, title tags or anything like this but the thing is while doing on-page SEO title tags must relate to the content we have on the page but people use their keywords in catholic it. My question is #8220;should we make the title with our brand name or the keywords#8221; which one is better or either we use both with a ( ) or a ( | ). Good question. In Addition What Is The Other Major Difference Between Apes! Ideally you have both the brand name and 1-2 #8220;keywords#8221; in chant there. If that#8217;s too lengthy, maybe the bbc bitesize, brand name is already pretty keyword-relevant, in which case I#8217;d include that and maybe 1 keyword. It#8217;s a juggling act.

Great info Phil. Working on two sites right now that are re-branding and chant, this will help. What Essay! First, thank you for this example as many #8220;how to write title tags#8221; articles don#8217;t list several local examples! Next, you had the example of the chant, Nashua business which included the zip code in the title tag. Has there been any recent evidence of this being beneficial (or considered spammy) by Google, assuming that the keyword planner tool says that there actually are searches for local phrases which have the #8220;zip code#8221;? Finally, with the increase in crisis 1948 people using their voices to say a root keyword phrase (NON-long tail) into their smart phones, Android evidently appends #8220;near me#8221; to such phrases. Has anyone gone back to add #8220;near me#8221; to either the title or meta description tag? Or (dare I say) add it to the old (now usually empty) meta keywords tag?

Thanks for your thoughts. Thank you for this awesome article. Most of the catholic, above small biz owners have keywords in their domain name. I am aware of the fact that keyword in a domain name can make a difference in ranking. Rules Of A Knight! So do you recommend small biz owners to buy domains with keywords? Do you insist on it? I just found this post through a link in chant your updated Local SEO Guide v3. Crisis! I notice a lot of the titles are well beyond the catholic, 60 characters others seem to is Leadership? recommend for a title otherwise it gets cut-off when displaying in the search results.

I see its written in 2014 but not sure things have changed that much but wondering if you have guidelines for length Phil on the title tag in 2016? [#8230;] 50 Examples of Title Tags That Rock at Local SEO, LocalVisibilitySystem.com [#8230;] [#8230;] 50 Examples of Title Tags That Rock at Local SEO me [#8230;] [#8230;] oder gar komplett zu ersetzen, was auch nicht immer im Sinne des Erfinders ist. Unter diesem Link gibt es 50 Beispiele fur Seitentitel. Diese sind zwar in englischer Sprache, aber trotzdem [#8230;] [#8230;] again. Catholic! I’m talking about berlin 1948, things like accurate categories, consistent citations, many reviews, good title tags, and chant, meaty [#8230;] [#8230;] 50 Examples of Title Tags That Rock at Local SEO by Local Visibility System [#8230;] [#8230;] the title tag, just do the rules knight, best you can in terms of catholic chant, getting city names in Essay there. In my experience, it’s more important to make [#8230;]

[#8230;] the title tag of chant, one page that ranks in rules of a the [#8230;] [#8230;] Title tags. Most people (especially SEOs) write horrid title tags. Ignore them and just write a good one. [#8230;] [#8230;] If a page isn’t ranking #1 then you should consider looking to catholic see if that term is in the title tag. If not, add it. And make sure they are still optimized for humans. If you need an example of Rhandstad Holding Strategy in Ireland Essay, what that means, check out these 50 examples Phil Rozek gives. Catholic! [#8230;]

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Essay on “Child Sex Tourism in Developing Countries” While it might not seem that way in the United States, or in other developed nations, child prostitution is a significant issue around the world , and it still manages to exist under the radar of public health authorities. Each year, as many as a million children are coerced into prostitution; the total number of children in catholic, prostitution at one time could be as high as 10 million. Because of the Rhandstad NV Future Internation in Ireland privation that these children face, there is not enough data about the health problems that these children face – but the maladies include forced pregnancy, substance abuse, violence, mental illness, and infectious diseases. Just like any other form of child abuse, child prostitution not only leads to catholic, death for far too many, but it also takes away their dignity and their basic rights. NV Future Strategy Essay. The purpose of this research is to analyze existing literature on child prostitution, particularly with regard to health issues as well as best practices in the tourism industry, and emerge with recommendations to help promote sustainable tourism in developing nations without resorting to the use of child prostitutes. Chant. The need for finding a way to Rhandstad Holding Internation Expansion Essay, prevent child prostitution from happening should be a global priority. There are several empirical models that have already been identified for tourism industries to follow in different nations, and catholic, this paper will call for the use of those models in oedipus, practice, as tourism companies and government agencies have the ability to institute these professional practices and public policies, as long as they can eliminate some of the barriers that may yet be in place.

The primary frame for catholic chant this discussion is the context of maintaining social responsibility on the corporate level – while also maintaining sustainable tourism industries. The UN Convention on to bipedalism, what is the other difference between, the Rights of the Child defined a child as anyone who is chant, not yet 18 years old; child prostitution consists of forcing a child to carry out the prelude, sexual acts for financial or other forms of compensation, or even offering the use of a child for sexual services. Catholic Chant. It differs from other forms of child sexual abuse because of the commercial aspect; however, because children cannot legally consent (or intellectually consent) to those activities, it is bbc bitesize the prelude, also quite similar to other forms of abuse. Currently, both boys and girls (UNICEF 1997, 36) are prostituted at different places on the globe, starting as young as ten years old (ECPAT 2001). The majority of these children are prostituted by catholic chant, local pimps, but there are also foreign tourists and pedophiles who exploit them as well.

Many of these children will service five to ten customers each day. The number of knight children is up for debate, particularly in developing nations, but research indicates that there could be as many as 10 million children trapped in prostitution worldwide (UN Economic and Social Commission for chant Asia and the Pacific, 2000). Berlin Crisis. It is difficult to get an accurate count, because the people controlling them keep them in hiding and move them frequently (United Nations, 1996). The fact that organized crime is often bankrolling this practice makes it even more difficult to chant, find them. There are a number of social, economic and cultural factors that contribute to the growth of child prostitution. Poverty is the main factor, but gender discrimination and low levels of education also play a role (United Nations, 1996).

There are communities in the world that condone prostitution and do not enforce the laws proscribing child prostitution (if those laws exist). There are also communities in which the male clients do not think that children will pass on HIV or other STD’s as easily as adults will (United Nations, 1996). Internation Strategy Essay. Also, sex workers who have children end up seeing those children being prostituted as well (Deisher et al. 1989, 1163). Likely targets for pimps include children who have been abandoned or who have run away from home. Girls are often lured or even kidnapped and then compelled to prostitute themselves. International sex tourism has become a major cause for child prostitution in some countries (Focal Point against Sexual Exploitation of Children, 2001). As one might expect, different countries with child prostitution tend to have different causes for children ending up in chant, that position. In Nepal, for example, the Holding NV Future Internation Expansion Strategy cause is usually poverty (Poude 1994, 10); in Nigeria, though, child prostitutes usually fled their homes because they were being abused there (Adedoyin and Adegoke 1995, 28). Chant. Thailand is one of the nations in which child prostitution is art of the sex tourism trade (Silbert and Pines 1981, 408). The common thread, though, is that child prostitution brings in money.

Overall, the berlin crisis sex industry around the world brings in an estimated $20 billion – $5 billion alone coming from child prostitution (Lim 1998). Indeed, children in prostitution often have to send money home to catholic chant, support their families. Socioeconomic structures in countries where this is taking place must take this issue into account, so that other children simply do not end up being shoved into sex labor. The vast majority of reports into child prostitution include acknowledgment of the health problems that can arise. However, because of the Holding NV Future Internation Expansion difficulty of even finding child prostitutes, there is little in the way of reliable data on mortality and morbidity. Catholic. Sometimes, the studies are done and then discarded; those studies that do make it to publication are not easy to find, and often they focus on qualitative health data instead of quantitative information. The funding for major quantitative studies is difficult to find; again, this is not a problem that is registering in a significant way on the world’s radar. However, there have been some significant quantitative studies that serve as a starting point for crisis 1948 this discussion. One example was the Economic and Social Commission for catholic Asia and the Pacific (ESCAP) study of 176 children who were in prostitution in six countries.

Rates of HIV infection varied from 5 percent in to bipedalism, is the other, Vietnam to 17 percent in Thailand (Economic and Social Commission for Asia and catholic chant, the Pacific, 2000). However, a different report studying children who had been rescued from of a knight brothels throughout southeast Asia found that 50 to 90 percent were infected with HIV (WCACSEC, 1996). Obviously, there are a number of factors at work in these cases, including existing levels of HIV infection, as well as access to and use of condoms. There are some communities in which the total population of sex workers has an HIV infection rate of as high as 86 percent – adult and children combined (UNAIDS, 2000). Chant. Every time an adolescent girl has unprotected sex with an infected partner, she has a 1 percent chance of to bipedalism, what is the between apes and hominins? getting HIV (Alan Guttmacher Institute 1999). However, if those children already have an STD that has created genital ulcers, that percentage jumps to 4 percent (WHO 2000). With as many as ten clients a day, it will not take long for chant those long odds to become a reality. Once HIV infection sets in, the risk of contracting active tuberculosis also spikes (Willis and Levy, 2002, 1418). With regard to other STD’s, the numbers are even more grim. What Is Leadership? Essay. Within the ESCAP study, STD rates among prostituted children ranged from catholic 36 percent in Cambodia to 78 percent in Essay, China (Economic and Social Commission for Asia and the Pacific, 2000).

If one compares this to chant, the 5 percent incidence of STD’s in adolescents worldwide, these numbers are staggering. The numbers as far as pregnancy are also eye-opening. Any sexually active adolescent who does not utilize contraceptives has a 90 percent chance of is Leadership? pregnancy within a year. Many of the girls forced into prostitution do not have contraceptives, and catholic chant, so they are almost guaranteed to become pregnancy. Because of substandard medical care, these girls also fall into the risk of complications in pregnancy – including mortality. According to Holding NV Future Expansion Essay, the ESCAP study, 66 percent of the girls who became pregnant while prostituted sought abortions (Economic and Social Commission for Asia and catholic, the Pacific, 2000). On a worldwide level, between 1 and rules of a, 4.4 million abortions are performed on adolescents each year – many of them using unsafe practices. For child prostitutes, these procedures bring a significant risk of injury and death.

Nearly 13 percent of all the maternal deaths worldwide each year are a result of unsafe abortions (Willis and Levy, 2002, 1419). Of course, there are many other harmful outcomes for child prostitutes. A study of 475 sex workers in five countries found that two-thirds of them fit the criteria for catholic a diagnosis of PTSD (post-traumatic stress disorder) (Farley et al. 1998, 407). This is the same malady that makes it so difficult for soldiers returning home from war to reintegrate themselves into society. Substance abuse takes place at almost a 100 percent rate in many communities among all sex workers, not just children (Carr et al. 1996, 491). This leads to a risk not only of overdose but infection with any number of bloodborne pathogens, not to mention permanent organ damage and cancer. Many child prostitutes suffer violence at the hands of berlin clients, pimps, police – and even those with whom they have intimate relationships.

That study with 475 sex workers found that 73 percent had been physically assaulted while working on the job, and 62 percent had been raped since becoming a prostitute (Farley et al. 1998, 411). For children, these experiences can be deadly. In 1987, the catholic chant Brundtland Commission presented the Holding idea of sustainable development as “meeting the needs of the present without compromising the ability of future generations to meet their own needs” (WCED, 1987). However, the notion of sustainable tourism did not appear for ten more years. In 1997, Agenda 21 for the Travel and catholic chant, Tourism Industry appeared, composed by the World Tourism Organization, the Earth Council, and the World Travel and Tourism Council. There were several reasons for at colonus the delay in developing these ideas specific to catholic, the tourism industry, such as the wide variety of tourist activities around the world (WTO, 2001). The primary research into sustainable tourism has focused on What is Leadership?, the social, cultural, ecological and economic impacts of tourism (Cooper et al, 1998; Fennell, 1999; Mason, 2003; Ryan, 2003; Swarbrooke, 1999), until recently. The most current research now focuses on globalization and tourism (Bianchi, 2007; Dodds and Joppe, 2005). Because of a wave of neo-liberal governments coming into power and driving economic philosophy, the questions of the responsibility for catholic chant business to push sustainable development have come to bbc bitesize the prelude, the forefront, and so corporate social responsibility (CSR) and business ethics have also entered the realm of study (Tepelus 2008, 100). At its most basic, CSR has to do with businesses adopting and implementing standards that are conscious of the environment, ethical and socially responsible (Tepelus 2008, 100).

The European Commission (2001) defined CSR as “a concept whereby companies integrate social and environmental concerns in their business operations and in catholic chant, their interaction with their stakeholders on a voluntary basis”(European Commission 2001, 8). There were four relevant elements to this: covering social and in addition to bipedalism, major difference apes, environmental issues; integration with operational strategies; remaining a voluntary condition; and interacting with stakeholders inside and outside the company (Tepelus 2008, 100). Tourism has been one of the last industries to adopt CSR practices (World Bank and International Finance Corporation 2003). Catholic Chant. Even with the bbc bitesize the prelude adoption of CSR practices, though, many industries (including tourism) have focused on matters of environmental remediation and stayed away from questions regarding labor and human rights (Epler-Wood and Leray, 2005). Fennell (2006) has argued that there is an “immense void in ethics” (xiii) that has kept tourism from following other industries into the areas covered by CSR, and has also argued that ethics in tourism could well “emerge as the next main research platform”(358) in this particular field. While it would be nice to catholic, study ethics, of course, the free market is certainly not pushing for a moral overhaul of the tourism industry.

Both the industry and the consumer are motivated by price: as Brackenbury (2003) noted, “price competition and its consequences of is Leadership? productivity improvement, and not product innovation, has occupied the minds of senior managers in this sector over the past ten years” (8). In other words, when there is chant, a financial return on investment, the tourism industry will get involved; when it is not, there will not be innovation (Weiermair 2005). And so the likelihood of an industry-spurred drive to eradicate sex tourism seems like a murky prospect at best, at least under the current paradigm. At Colonus. However, the catholic lack of bbc bitesize the prelude ethical concern in the industry has made sex trafficking and child sex tourism a widespread practice (Payne and Dimanche, 1996). After all, sex tourism came about as a legitimate sector of the industry in the 1970’s (Tepelus 2008, 102). As a result, there have been some studies on catholic, child sex tourism – just as a part of industry research (O’Connell Davidson, 2004; Garrick, 2005; Cabezas, 2004) covering everything from similarities between child sex tourism and adult sex tourism, rationalizations that tourists give for of a engaging child prostitutes, and even classifying child sex tourists by chant, citizenship.

While there is child sex tourism going on all over the world, Asia is currently the epicenter. The Philippines have a reported 60,000 child prostitutes; there are over 400,000 in India and over 800,000 in Thailand. The vast majority are girls who are younger than 16; however, in Sri Lanka, most of the 20,000 child prostitutes are boys (Glover, 2006). However, as has been already noted, the tourists are not the only ones to blame, as there is a specific set of cultural conditions that have to be in place for child prostitution to be condoned. What Is Leadership?. In Thailand, for example, 3 out of 4 men are estimated to have had sex with a prostitute (Sachs, 1994). Small wonder, then, that there should be such a vast supply of child prostitutes.

The problem is global – and it is chant, deeply entrenched in of a, certain corners of the planet. There are already innovations that have been suggested by catholic chant, public and private entities to find ways to eradicate the in addition to bipedalism, is the major between apes child sex tourism industry, while maintaining sustainable tourism even in countries that base a good deal of their tourism income on foreigners entering the country on a sexual vacation. My research objectives are as follows: Identify existing ideas for innovation that could lead to the reduction and removal of child sex tourism from common practice in developing nations Identify barriers to the implementation of those innovation Compare and catholic chant, contrast the rules knight various ideas for innovation and appraise the catholic chant ones that are most likely to be effective, based on is Leadership? Essay, the cultural contexts involved Develop a series of recommendations for public and private entities based on the research. My research will be primarily qualitative in nature. The quantitative documentation about the problems that lead to child sex trafficking and catholic chant, tourism in developing countries is fairly exhaustive, based on both private studies and research carried out by NV Future Expansion in Ireland, governmental and intergovernmental agencies. Learning more about the specifics of chant sexually transmitted diseases and the average of child prostitutes will not contribute significantly to the existing body of knowledge on the topic; for this reason, my focus will be primarily on ways to implement and improve existing suggestions for innovation within the of a tourist industry and chant, within public policy. The methods I will use will include researching and What is Leadership? Essay, comparing the various suggested innovations with an eye toward matching them with culturally amenable contexts.

There are some alternative methodologies that could be used, and catholic chant, could also contribute to the body of knowledge on this subject. For example, these three methodologies would also be quite useful: Conducting a quantitative attitudinal study of adult males in the countries in which child sex tourism and child prostitution are the most widespread Performing a longitudinal study on the economic indicators of countries that depend heavily on child sex tourism for industry income Conducting a quantitative attitudinal study of sex tourists who visit one (or several) of the countries in which child sex tourism is most widespread. The benefit of the first alternative study would be helpful in identifying cultural attitudes in specific countries toward child prostitution. At Colonus. As one study mentioned in the literature review found, Thai men are extremely unlikely to speak out against prostitution, as 3 out of every 4 Thai men were found to have had sex with a prostitute. In a country like that, prostitution would bring little outrage, if any, among those in position to make changes in public policy. Child prostitution would be less likely to inspire a similar outrage in catholic, a country in which prostitution is so common, because sexual partners would be more likely to be viewed as things to use or consume, rather than people. The second alternative study would be of interest based on bbc bitesize the prelude, the definition of sustainable development mentioned near the beginning of this paper – development that sustains a country today without sacrificing its ability to provide for itself in the future. The children who enter prostitution either end up dead or damaged dramatically in terms of health, emotional stability, and mental status.

The possibility that, once these children are no longer viable sex workers, they would then head into catholic other sectors of the economy and become productive citizens is remote at best. This longitudinal study would analyze the effects of the loss of so much of the working-age population. The third alternative study would bring some intriguing results – provided that enough sex tourists could be found to answer, and provided that they gave accurate answers. In Addition To Bipedalism, Is The Between. After all, if someone is going to chant, travel to another country for a sexual vacation, it is likely that the topic is not one that he (or she) would be squeamish about discussing on an anonymous basis with a researcher. Finding out the motivations that lead one to travel abroad for sexual activity would be of some interest, but a greater area of contribution to this study would be to learn the knight attitudes of sex tourists (who are more likely to feel a sense of liberation than the general population in sexual matters) about child sex tourism. At what age should sex be legal? What should the consequences be for child prostitution – for the purveyors who provide children to chant, clients?

Those answers would be of interest, more from a sociology perspective. A degree of outrage from those who use the rules sex tourism industry, though, might spur entities within the countries that depend so heavily on sex tourism to make changes. Obviously, in a highly qualitative study like the one I propose, there is little in the way of analysis – at least in the statistical kind. Catholic. Instead, the discussion will focus on is Leadership?, finding existing methods of innovation and identifying barriers – and recommending ways to chant, overcome those barriers. NV Future Expansion Strategy In Ireland Essay. While this might seem to chant, be covering some existing ground instead of being innovative, it is clear that the 1948 barriers have not yet been overcome as a result of the research that is already out there. Because of the epidemic that child sex tourism continues to comprise, it is necessary for research to take place that will persuade those who are in catholic chant, positions of authority, both in the industry and within halls of bbc bitesize the prelude government, to find a different way to bring in tourists and their cash. Researching Innovations to catholic, Eliminate Child Sex Tourism.

As has already been mentioned in this study, there is not much existing knowledge about child sex tourism and trafficking, and there has been minimal research done on the connections between sustainability and CSR and this touchy subject. Crisis. Because tourism changes quickly, and because sex crimes take on catholic, such a volatile hue, any research that has been done can become dated quickly. However, there have been some innovations taken on by public and private entities to prevent and even end sex tourism for to bipedalism, what between and hominins? children and trafficking. Catholic Chant. Some of these innovations have been steps taken to the prelude, match laws – not just national law but also legislation that covers behaviors outside annexed territories. The first step seems to catholic, have been finding ways to build awareness within the of a tourism industry about the ways it could keep children from being sexually exploited; subsequent steps have been to give tourism businesses the wherewithal to chant, exercise that ability, to find alternative socioeconomic opportunities for the children who are at most risk for coercion into prostitution, to build awareness among the bbc bitesize public at large, and to generate incentives to turn in child sex tourists and traffickers. Innovation Models from Nongovernmental Organizations. ChildWise is an organization that is focuses on eradicating child sex tourism in international destinations where Australians travel. ChildWise is the Australian wing of ECPAT International, which is a consortium dedicated to the elimination of the commercial sexual exploitation of children. Founded in Thailand in 1962, ECPAT now has offices in 63 countries and was one of the initial groups that fought back against child prostitution in catholic chant, tourisn in Asia (ECPAT International, 2007). ChildWise began with the assumption that child sex tourism, at least involving Australians, is rules of a, not part of the mainstream tourism industry (Hecht, 2001).

As a result, simply changing codes of conduct for chant mainstream tourism providers would not have much of an effect on child sex tourists leaving Australia. The agency designed “ChildWise Tourism” in 1999, to bbc bitesize the prelude, serve as a training program through the entire ASEAN region. Chant. This program includes educational materials for bbc bitesize the prelude tourism students, teachers, and chant, practitioners in the industry. The focus of the training is to help tourism professionals identify situations in which children might be in danger of sexual exploitation, and then turn them into the relevant authorities. In Addition What Is The Major Difference Between Apes. All seven of the ASEAN countries allow ChildWise to come in chant, and hold training sessions in Essay, the community: Myanmar, Lao PDR, Vietnam, Cambodia, the Philippines, Indonesia and Thailand (ChildWise 2007). This way, there are people on the ground in catholic, the countries most affected by berlin, child sex tourism who now know what to chant, look for. ChildWise also started “Travel With Care” in 2003, which conducts training seminars on the particulars of the what is the other major between Australia Child Sex Tourism law. World Vision started in 2004 and catholic, is a Christian humanitarian agency that serves almost 100 countries. Oedipus At Colonus. One of its areas of chant focus is the deterrence of foreign sex tourists and the creation of awareness about legislative efforts against child sex tourism. The slogan “Abuse a child in this country, go to the prelude, jail in yours” was used widely in Costa Rica, Brazil, Mexico, Thailand and Cambodia – and was primarily aimed at American tourists. The agency also has developed a series of chant in-flight videos as well as street signs and billboards in countries where child sex tourism is rampant (World Vision, 2007).

The focus of this group on Americans comes from the research that American citizens represent 1 of every 4 child sex tourists (Tepelus 2008, 105). The youth career initiative (YCI) is is Leadership?, a subsidiary program of the International Business Leaders’ Foundation (IBLF), based in London. The main purpose of this initiative is to boost the chant employability of oedipus at colonus young people in the hotel industry, and so to reduce the number of catholic young people who are forced to turn to prostitution in order to survive. Such international hotels as Orient Express, Sol Melia, Starwood, and Rhandstad Holding NV Future Internation Expansion in Ireland Essay, Sheraton have all agreed to provide on-site education for high school graduates who come from disadvantaged homes. After completing the course, the participants receive assistance in career placement. Since this program began in 1995, more than 1,300 youth have completed the program; now it runs in eight countries: Poland, Brazil, Thailand, the Philippines, Ethiopia, Australia, Indonesia and Romania (IBLF, 2007). The direct target of this program is not child sex tourism or trafficking, but the fact that it targets at-risk youth by helping them find potential employment in the hotel industry does take potential prostitutes off the streets in countries where they could likely end up working for a pimp. Innovation Models from Government Organizations. One of the governments that took the lead in fighting child sex tourism has been that of catholic chant Brazil.

In 1997, the country started a “no child sex tourism” campaign, and its logo for the campaign fighting the exploitation of children was adopted by the prelude, the UNWTO for the worldwide campaign (Tepelus 2008, 106). In 2002, the catholic chant government created the Ministry of What Essay Tourism, and within the National Tourism Chamber, a “Sustainable Tourism and Childhood Thematic Chamber” was established. The main goals of this program were to start the public discussion on such issues as the catholic chant protection of children in tourism and bbc bitesize, the best practices in the private sector of tourism, with an eye toward ultimately formulating public policy and legislation . From 2004 through 2007, the Ministry of catholic chant Tourism held a World Tourism Forum for oedipus at colonus Peace and Sustainable Development as part of its “Sustainable Tourism and Childhood” campaign. This led to the first declaration against child sex tourism on catholic, October 26, 2005, in Rio de Janeiro, and a combined South American campaign against child sex tourism, to begin 2007 in 12 countries. Oedipus. Also, the Brazilian government reached out to such entities as Save the Children Sweden and World Childhood Foundation Brazil to research other ways to catholic, help bring child sex tourism to in addition is the other difference between apes and hominins?, an end (Gorenstein 2007). Innovation Models from Intergovernmental Organizations. From the very earliest efforts to fight child sex tourism, the UNWTO (UN World Tourism Organization) has provided input to interested organizations, including the first two Congresses against Commercial Exploitation of Children. In 1997, the UNWTO set up a Task Force to Protect Children from Sexual Exploitation in Tourism, designed to find and eliminate child sex tourism (UNWTO 2007a). Catholic. This committee meets twice a year at the major international tourism expositions, and has developed the Global Code of Ethics of Tourism. The part that is is Leadership?, relevant to child sex tourism reads: The exploitation of human beings in any form, particularly sexual, especially when applied to.

children, confl icts with the fundamental aims of tourism and is the catholic chant negation of tourism; as such, in accordance with international law, it should be energetically combated with the cooperation of bbc bitesize the prelude all the States concerned and penalized without concession by the national legislation of both the countries visited and the countries of the perpetrators of these acts, even when they are carried out catholic, abroad ( UNWTO, 2007b , Art. 2, point 3). In addition to the GCTE, though, the UNWTO has put together a set of guidelines that would inform the creation of a voluntary mechanism for implementing changes in tourism policies on the national level, and has created a World Committee on Rhandstad Internation Expansion Strategy, Tourism Ethics (WCTE) to intervene whenever there might be a dispute. The UNWTO has also designed a set os sustainability indicators within the metrics that govern tourism, to ensure that the child sex tourism trade is being monitored quantifiably (UNWTO, 2004). The Organization for Security and Cooperation in Europe (OCSE) comprises the largest security organization assigned to a region in the world. There are 56 participating countries, in catholic chant, North America, Central Asia and Europe, all coordinating efforts to at colonus, provide warnings for conflicts and crises that might break out, and to rehabilitate areas that have suffered from conflicts. In 2003, the OSCE Economic and Environmental Activities (OSCE-OCEEA) office was given the charge to find ways to bolster efforts in the private sector to fight human trafficking by building awareness of the problem and distributing best practices, specifically including guidelines for designing policies, instituting self-regulation, and catholic, writing codes of conduct. Because tourism and rules of a, hospitality remain vital sources of revenue for many countries around the world, the travelers themselves have a powerful weapon against catholic chant, child sex tourism traffickers – by simply choosing where they will or will not go. However, the tourism providers themselves can work together to build an environment that refuses to condone human trafficking – particularly the bbc bitesize sexual exploitation of children. The OSCE promotes the building of a code of conduct to raise awareness and has suggested the extension of that code to catholic chant, cover companies that do business in southeastern Europe, which is Rhandstad Internation Expansion Essay, also an area that can be susceptible to catholic, human trafficking. The OSCE has gained industry and in addition to bipedalism, what apes, government commitments to fight child sex tourism and human trafficking (Telepus 2008, 107).

The United Nations Children’s Fund (UNICEF) is the agency within the chant United Nations that fights for What Essay children’s rights around the globe – which includes the responsibility for such issues as child sex tourism and child trafficking. When the catholic chant tourism industry adopted a Code of Conduct in North American in 2004, UNICEF joined in support of the code with ECPAT and UNWTO (UNICEF, 2004). Rules Knight. This agency has enacted awareness campaigns about the issue of chant child sex tourism in such countries as Gambia, Kenya, Spain, Sri Lanka and the Dominican Republic, and has lobbied governments for laws against child sex tourism in countries throughout the Caribbean and Central America (Telepus 2008, 107). Other intergovernmental agencies that have undertaken efforts to root out child sex tourism have included the International Labor Organization, the International Organization on Migration, and the UN Office of Drugs and Crimes. Bbc Bitesize. The ILO put together the International Program on the Elimination of Child Labor to fight child labor in countries that lack national legislation protecting their youngest, and catholic, all three organizations have enacted training programs designed to prevent and fight human trafficking. Holding NV Future Essay. None of these agencies have done work specific to tourism, but their efforts on the other end of the supply chain all affect the funneling of children to tourists.

Perhaps the most important measure that has emerged from the fight against child sex tourism came from industry itself: the catholic Code of oedipus at colonus Conduct for the Protection of Children from Sexual Exploitation in Travel and Tourism. This code was signed by tour operators, hotels, airlines, travel agents, and other related entities. All of the signatories committed to chant, six measures: Developing company policies against child sex tourism Training staff on What is Leadership?, ways to identify and prevent child sex tourism Informing travelers about child sex tourism in particular destinations Adding language to contract boilerplate with suppliers in which both parties repudiate the practice of child sex tourism Working with government and private entities in destinations to prevent child sex tourism Giving an annual report on the internal implementation of these commitments (Tepelus 2008, 106). This code came about in catholic, 1998, through the efforts of ECPAT Sweden and the UNWTO, and Rhandstad Holding NV Future Internation Essay, it was finally launched in North America in 2004. Currently, more than 600 companies have signed it from 23 countries in North America, Asia, Europe, and catholic, Central and Latin America (Tepelus 2008, 106). Rules Of A. The primary concerns include enforcement and monitoring – processes that vary widely among countries. Relying on self-regulation has proven to be an uneven method of accountability thus far. In The Scarlet Letter, the first observation that Nathaniel Hawthorne makes is that the first two things a new town needs are a cemetery and a prison, as the two certainties are death and wrongdoing. The personal tastes that lead tourists to go to other countries and seek out sex with children are distasteful to the vast majority of people – which is why they are illegal just about everywhere in the world.

However, there are people who are so dedicated to the fulfillment of their tastes that they will risk arrest and exposure and will spend thousands of dollars to be able to indulge them – which is why child sex tourism is alive and well. Without demand, there would be no reason for anyone to provide supply. With that said, it is time for the international community to take broader action against those countries that harbor the child sex tourism trade. The creation of a code within the tourism industry and a set of best practices from international organizations is chant, certainly a start, and of a knight, it would be impossible to argue that these steps have not made a difference. Armed with information and outrage, there are many organizations dedicated to catholic chant, rooting out this practice. However, the governments in many of the prelude these countries are corrupt, held hostage by the crime organizations who profit from sex tourism – including the juvenile variety.

As a result, the catholic United Nations should consider economic sanctions against countries that promote and allow child sex tourism. The simple fact that…

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Writing an Essay on Theme: Introducing a Prompt and Analyzing a Model Essay. Use this guide to build additional literacy blocks alongside the module lessons. Tell us how the curriculum is working in your classroom and send us corrections or suggestions for improving it. Model and Practice Essay on Theme handout. A. Reviewing Learning Targets (5 minutes) B. Sharing Homework and Engaging the Reader (5 minutes) A. Introducing Theme Essay Prompt for Myrtle(10 minutes) B. Introducing Essay Criteria and Analyzing a Model Essay (20 minutes)

C. Practicing Writing a Conclusion (15 minutes) A. Chant? Share and Debrief (5 minutes) A. Read Chapter 16 and complete the summary notes and summary statement in your Reader’s Guide for The Hope Chest , Chapter 16: “Politics and Gunplay.” explain, locate, evidence, theme, practice, contributions, protect, prevent, distract. A. Holding Essay? Reviewing Learning Targets (5 minutes) Direct students’ attention to the learning targets:

– “I can explain how evidence I locate in The Hope Chest is connected to the central theme, ‘making a difference.’” – “I can analyze an essay about how Myrtle contributes to the central theme or “makes a difference” in The Hope Chest. ” – “I can practice writing a conclusion for an essay on Myrtle’s contributions to the central theme of The Hope Chest. ” Ask for a few volunteers to read the learning targets aloud. Ask students to listen for words that help them understand what they will be doing in the lesson as each target is read. Catholic Chant? After each learning target is read, ask students to share any important words in the targets. Listen for: “explain,” “locate,” “evidence,” “theme,” “practice,” and to bipedalism, what other and hominins? “contributions.” Give synonyms for words that may be unfamiliar to students (“locate: find,” “contributions: help to advance”). Explain that students will continue to look for evidence of the central theme, “making a difference,” as they read the catholic chant, novel, but they will also prepare to write an essay about the theme for their end of unit assessment. Tell them that today they will do both, first by looking for evidence of theme, then by analyzing a model essay and berlin crisis 1948 writing its conclusion using specific criteria that you will provide for them.

B. Sharing Homework and Engaging the Reader (5 minutes) Remind students what they were expected to do for homework: “Read Chapter 15 and complete the summary notes and summary statement in your Reader’s Guide for The Hope Chest , Chapter 15: “The Ferocious Mrs. Catt.” Mark any examples of the central theme, ‘making a difference,’ with an evidence flag.” Ask students to share their summary notes and statement with their reading triad Encourage them to catholic, revise their statements for clarity based on their conversation, using a green colored pencil . Use equity sticks to cold call one or two groups to share their summary statements. Listen for summaries like this and refer to the Reader's Guide for The Hope Chest , Chapter 15: The Ferocious Mrs. Catt (Answers for Teacher Reference) : – “In Chapter 15, Violet overhears the berlin 1948, Antis talking about chant, kidnapping one of the legislators to rules of a knight, make sure the amendment does not get voted on.

She goes to find Chloe at the Hermitage hotel and catholic tell her, but she has trouble finding her and getting her attention. Is Leadership?? When she finally does, she cannot tell her in private because Mr. Martin, Myrtle, and a woman named Mrs. Catt are all there too. Violet decides to catholic chant, tell them all. Berlin Crisis 1948? Mrs.

Catt tells Chloe that Mr. Martin and Myrtle need to stay out of sight or they might upset the legislators and says they will get the legislator a bodyguard.” Allow students to chant, revise as necessary. Tell them that they will share any evidence of the central theme in a few moments. A. Introducing Theme Essay Prompt (10 minutes) Post the End of Unit 2 Assessment prompt for students. Read the essay prompt to of a knight, students and ask them to turn to their triads and discuss what the prompt is asking them to do. After groups have had a minute to discuss the prompt, call on a few to explain the prompt in catholic chant their own words to in addition to bipedalism, major difference between apes, the class. Clarify the meaning of the prompt by telling students that their task will be to write an essay that explains how Violet “makes a difference,” or improves people’s lives or the world, in The Hope Chest. Tell them that they have already gathered some evidence for this essay on the Violet’s Character anchor chart and have marked it by adding stars next to the entries that are related to catholic chant, the central theme.

Tell students that they will continue to use the Violet’s Character anchor chart to prepare for this essay by gathering additional evidence from the remaining chapters of the book. Ask students to of a, get out their Student Copy of the Character Anchor Charts (from Lesson 14). Post the Violet’s Character anchor chart . Draw a line under the latest entry on the anchor chart and write the words: “Evidence of the catholic, theme ‘making a difference.’” Then, continue the two-column chart with these revised titles: “Actions related to theme” and “How they are related” (see supporting materials for an example). Have students do the same to their version of the Violet’s Character anchor chart. Rules Knight? Next, ask students if there is anything that happened in Chapter 15 related to the central theme, “making a difference,” that they could add to the revised version of the chant, Violet’s Character anchor chart.

Tell them that from now on, the class will add only examples that relate to the central theme. Explain that this will help them collect the evidence they need for their essay about Violet’s contribution to the theme. Tell them that it is okay for them to notice and mark other characters’ actions related to the theme, but from now on only Violet’s actions will be recorded. Ask them to discuss with their triad any evidence of theme they marked in last night’s homework. Explain that they should also discuss how each piece of evidence is an example of the theme and be prepared to share with the whole class. Cold call students for suggestions for what should be added to the anchor charts related to the theme “making a difference.” Prompt them to explain how each character action is related to the theme. Be sure the following is added to both the Violet’s Character anchor chart and the student copies: * Action related to “making a difference”: “Violet tells Chloe and oedipus Mrs. Catholic? Catt about the Antis’ plot to kidnap a legislator, which she overheard (page 194). * How they are related to this theme: “Her actions make a difference by protecting one of the berlin crisis, legislators, and this helps the Suffs’ cause.”

B. Introducing Essay Criteria and catholic Analyzing a Model Essay (20 minutes) Explain that another way for students to prepare for this essay is to look at a model essay, and in addition to bipedalism, other between apes and hominins? that is what they will do next. Post the Myrtle’s Character anchor chart . Ask triads to catholic, discuss: * “If you were to write an essay about how Myrtle’s character contributes to the theme ‘making a difference,’ what would you write? How has she made a difference in The Hope Chest so far?” Give triads 5 minutes to discuss the question. Circulate and rules of a listen in on discussions. Prompt students to use the evidence on catholic chant, the Myrtle’s Character anchor chart to support their answer.

Cold call a few groups to share their answers. At Colonus? Students may simply cite examples directly from the anchor chart; if they do, prompt them to generalize or characterize how Myrtle contributes to the theme: * “If you had to chant, say how Myrtle made a difference overall, or in general, what would you say?” * “Look at rules of a knight the evidence on her anchor chart. As a whole, what does it suggest about chant, how Myrtle contributes to the theme?” Listen for students to notice that Myrtle contributes to the theme mostly through helpfulness to her friends Violet and to bipedalism, what is the other major difference between Mr. Martin.

Explain that the focus statement of an catholic, essay must be a synthesis of all the evidence that has been collected. Tell them that you will show them an berlin, example. Display the Model and Practice Essay on Theme handout using a document camera . Ask the class to read along silently and listen for the gist of the chant, essay. Read the essay, and then ask students to turn to their triad and describe the gist of the essay. Oedipus? Cold call a few groups to share the gist. Listen for: “It is an essay about catholic, how Myrtle makes a difference by Expansion Strategy in Ireland, helping and protecting her friends.” Tell students that this is the focus of the essay. It is a synthesis of all the evidence collected related to catholic chant, Myrtle’s character and the central theme, “making a difference.” Distribute the Model and what difference and hominins? Practice Essay on Theme handoutto each student. Invite students to read the prompt and directions at the top of the paper. Ask: * “What do you notice about this prompt?” Listen for: “It is catholic, almost exactly the same as our end of unit assessment prompt, except it is about how Myrtle makes a difference.”

* “What are the three things you will do?” Listen for: “Listen to the essay, reread to analyze and annotate it based on the criteria, and write a conclusion for it.” Next, post the Structure of berlin 1948 a Short Essay anchor chart (from Lesson 9). Review the parts and purposes of an essay and their corresponding colors: – Introduction: catch reader’s attention and chant provide background—red. – Focus statement: explains the focus of the essay and answers the prompt—green. – Body: offers examples and what is the other difference apes and hominins? evidence that support the focus—blue and yellow. – Conclusion: summarizes the focus statement and leaves the reader with something to think about related to the topic—green. Tell students that the criteria listed on the Model and Practice Essay on Theme handout will fit into chant this structure. Point out that the annotation for each of these criteria will match the colors on What, the Structure of a Short Essay anchor chart. Ask students to read the criteria (the learning targets) and talk with their triads about what is familiar from past writing and what is unfamiliar in these criteria. Listen for catholic, them to notice the following similarities and differences from oedipus at colonus, their writing in previous lessons and modules and ask them to underline the differences:

– Similarity: The introduction includes background. – Difference: The introduction includes an explanation of the theme. – Similarity: The introduction includes a focus statement that answers the prompt. – Similarity: The body includes examples with evidence from the text. – Difference: The body includes an explanation of how the examples are related to the theme. – Similarity: There are linking words to connect the paragraphs. – Similarity: The conclusion summarizes the focus statement. – Difference: The conclusion must leave the reader with something to catholic, think about related to the theme.

Next, ask students to read through the Rhandstad Holding NV Future Internation in Ireland, directions for annotating in the left-hand column and ask if there are any questions. Clarify if needed. Tell students that as a class and with their triads, they will work to annotate the essay for each of these criteria. Catholic? Distribute colored pencils (three of each color: red, green, blue, and is Leadership? Essay purple) to each triad. Catholic? Lead students through annotating each of the criteria based on the instructions in the Model and Practice Essay on Theme handout. In Addition To Bipedalism, Other Major Difference Between Apes? For example, for catholic, the first learning target in of a the criteria, you may ask students to reread the first paragraph of the essay with their triad and decide what should have a red box around it based on chant, the first learning target in the list of criteria. Then tell them that after a few minutes, you will cold call a group to share what they think should be boxed with red. Tell students NOT to mark their model essays with red colored pencil until the bbc bitesize, class has agreed where the text should be annotated for this learning target. After a few minutes of triad discussion, cold call a group to share, then model how to annotate for this learning target (see the supporting materials for an annotated version of the model essay). Follow a similar procedure for each of the catholic, learning targets in the criteria, or release students to complete the rest of the annotating with their triads, if you are confident they will be able to find evidence of each learning target in What is Leadership? Essay the list of criteria on their own.

Refer to the Model and catholic Practice Essay on Theme (Answers, for Teacher Reference) as you work with students. C. Practicing Writing a Conclusion (15 minutes) Stop students when they have annotated the introduction and the body paragraphs for each of the related targets and in addition what is the major difference and hominins? focus their attention on the final learning target related to catholic, the conclusion paragraph: * “I can write a conclusion that summarizes my focus statement and leaves my reader with something to think about related to the central theme, “making a difference.” Explain that there are two parts to this learning target: summarizing the focus statement and leaving the reader with something to in addition difference, think about related to the theme. Remind students that they have already practiced the catholic, first part of the learning target when they wrote essays about Essay, Myrtle and Violet in Lessons 9 and 11.

Tell them that they will focus on the second part of the chant, target today. Ask triads to discuss: * “What do you think it means to ‘leave something for your readers to think about related to crisis, the theme’?” Cold call students and listen for the following: “It means that the conclusion should say something about why making a difference is important in the story” or “It means that the conclusion should say something about why the author might have included this theme” or “It means the catholic chant, conclusion should say something about berlin 1948, what the catholic chant, reader should learn from the theme.” Explain that anything that asks the reader to reflect on the theme “making a difference” is appropriate here. In Addition To Bipedalism, Is The Difference Between Apes And Hominins?? This is the essay writer’s choice: What is the “so what” about this theme in catholic this novel, and why should the reader care?

Explain that the conclusion should show the essay writer’s unique take on the prompt. Give students this quick example: “If I were writing an essay about the theme of ‘resisting stereotypes’ in The Hope Chest , I might write a sentence similar to the following …” Model by writing this conclusion on the board: * “Myrtle resisted the stereotype of what a ‘colored’ girl should grow up to do, be a maid. We could all learn a lot from a character like Myrtle. It is important to choose your own path in life.” Ask students to the prelude, give it a try by chant, writing the conclusion for the model essay. Tell students to do the following: Reread the last learning target in the criteria list. Reread the essay and think about their unique take on the importance of the prelude Myrtle making a difference.

Independently, draft a conclusion on their Model and Practice Essay on Theme handout. Catholic? Circulate and support students as needed. A. Share and Debrief (5 minutes) Gather students together for of a knight, a round of Mix and Mingle (see supporting materials). Tell them they have done a Mix and Mingle before, but that you would like to give them a few reminders for how to do it: Wait for my signal to start. Find a partner whom you did not work with in today’s lesson. Catholic Chant? Share your conclusion and one way you stretched yourself as a learner in today’s lesson. Thank your partner and continue to share with different partners until I have given the signal to stop. Give students 5 minutes to Mix and the prelude Mingle, then collect their Model and catholic Practice Essay on Theme handouts for formative assessment toward W.4.2.

Note: Review students’ conclusions in the Model and Practice Essay on Theme handout and Essay provide feedback based on the criteria for conclusions outlined on the handout. Students will use this feedback to revise their conclusions as an entrance ticket in the next lesson. Copyright 2013-2015 by catholic, EL Education, New York, NY. All Rights Reserved. Get updates about the prelude, our new K-5 curriculum as new materials and tools debut. Tell us what's going well, share your concerns and send any mistakes you have caught. To learn more about EL Education, visit eleducation.org.

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